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Database: UniProt
Entry: A0A0G3I4U1_LIBAF
LinkDB: A0A0G3I4U1_LIBAF
Original site: A0A0G3I4U1_LIBAF 
ID   A0A0G3I4U1_LIBAF        Unreviewed;       508 AA.
AC   A0A0G3I4U1;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   23-MAY-2018, entry version 20.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AKK20280.1};
GN   ORFNames=G293_03260 {ECO:0000313|EMBL:AKK20280.1};
OS   Candidatus Liberibacter africanus PTSAPSY.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Liberibacter.
OX   NCBI_TaxID=1277257 {ECO:0000313|EMBL:AKK20280.1, ECO:0000313|Proteomes:UP000035503};
RN   [1] {ECO:0000313|Proteomes:UP000035503}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PTSAPSY {ECO:0000313|Proteomes:UP000035503};
RA   Lin H., Pietersen G., Sahota P., Lou B., Han S., Read D.A.,
RA   Civerolo E.L., Gupta G.;
RT   "Complete genome sequence of 'Candidatus Liberibacter africanus,
RT   bacterium associated with citrus huanglongbing'.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00747961}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP004021; AKK20280.1; -; Genomic_DNA.
DR   EnsemblBacteria; AKK20280; AKK20280; G293_03260.
DR   KEGG; lau:G293_03260; -.
DR   PATRIC; fig|1277257.4.peg.700; -.
DR   KO; K02313; -.
DR   Proteomes; UP000035503; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000035503};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00747973};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035503}.
FT   DOMAIN      201    332       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      416    485       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     209    216       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   508 AA;  57564 MW;  47D0DBFDF01FC8FD CRC64;
     MEGIKMQLRG ISACIQENDE MAAKIPQTDN DTRCLAIKCE SFFTTVSSRL KNQVGPDVYA
     SWFQRLKFHS VSHNIVHLSV PTNFLKAWIK NRYLETITRL FQEESSNIQG VEILVRSVAL
     VPTEQLVASH SHASTKPSSI NPNTGKGNFP TGKQTTNPIF GSPLDNRFVF STFIEGPSNR
     VALTAAKNIA ELDSNGYTTV RINPLFIHAS VGLGKTHLLQ AVANAAIKKQ PNLRVVYLTA
     EYFMWRFASA IRDNYALNLK DSLRNIDLLL IDDMQFLQGK LIQHEFCHLL NSLLDSAKQV
     VAAADRPPSE LESLDPRIRS RLQGGVAVPL GSHDYEMRFS ILKNRLSISQ KEDPKLIIND
     EVLMHVARTV TTSGRELDGA FNQIVFRHSF EPVLTVEIVD ELLSHLVNTG ETKKMRIEDI
     QRMVSKHYNI SRNDLLSNRR VRTVVRPRQI AMYLSKIMTP RSFPEIGRRF GDRDHTTVLH
     AVRKVEKMLE TDITLKKEVE LLKRLISE
//
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