ID A0A0G3UIX2_9ACTN Unreviewed; 1089 AA.
AC A0A0G3UIX2;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cell division protein FtsK {ECO:0000313|EMBL:AKL66342.1};
GN ORFNames=M444_14080 {ECO:0000313|EMBL:AKL66342.1};
OS Streptomyces sp. Mg1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465541 {ECO:0000313|EMBL:AKL66342.1, ECO:0000313|Proteomes:UP000035653};
RN [1] {ECO:0000313|EMBL:AKL66342.1, ECO:0000313|Proteomes:UP000035653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL66342.1,
RC ECO:0000313|Proteomes:UP000035653};
RX PubMed=23908282;
RA Hoefler B.C., Konganti K., Straight P.D.;
RT "De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using PacBio
RT Single-Molecule Sequencing.";
RL Genome Announc. 1:e00535-13(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; CP011664; AKL66342.1; -; Genomic_DNA.
DR RefSeq; WP_037797671.1; NZ_CP011664.1.
DR AlphaFoldDB; A0A0G3UIX2; -.
DR KEGG; strm:M444_14080; -.
DR PATRIC; fig|465541.12.peg.3048; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000035653; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR032030; YscD_cytoplasmic_dom.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR Pfam; PF16697; Yop-YscD_cpl; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:AKL66342.1};
KW Cell division {ECO:0000313|EMBL:AKL66342.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000035653};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 123..173
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 765..1004
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 203..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 783..790
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1089 AA; 109984 MW; C4B25A0A258C4584 CRC64;
MQIRLTVLGS RSGHQTATAP TSCDVLVTAP AGTALAAVAS GLAATVGGPD TGGTVVLYAG
AERLDPQRRV LGEPPLVDGA VLALHGPVPD VLPDAEEGLG TPQLHVVAGP DAGGVHLLHP
GAVRIGRSAD ADVPLDDPDV SRAHCAVTVM PDGRVAVADL NSTNGTTLDG VAVGERAVAL
APGALLRVGE STLRLTVGAS IPLPVTPDQE GHLSIPPARP SAAGAPGDGR GGAYPDARRA
DGSAGGYAGS RSGAQGLLPH PAPSSNGGSA PGPTSGPGPG TPHPDAPVAG PRGAAHPAGP
AADPMPQRGG APGPARPARP DAAGPARPGA GHFGAAPEPG ANRFSAGSEP GAGRPGAAPE
SGADRFSAGP EAGAGRFGAG SEAGGGGEGA RRRGIGAWAR KWVRGEQAGQ AEDVRAAAAA
VSARPAADDP AALLLAALGP TRRLWSRRPG ALDVGLGAGC RVAFQDVGAL GVAGPRARLT
GVARSVIAQL AALHAPAQLE IVLISTDRAR ALADRRRDWG WLGWLPHLRP AHGQDCRLLL
AYDRDQAAAR AGELTRRLDD GPLGTGWASA DRAAIREAAA AYEGPYTLLV LDGDPGTGAL
RDVTARLASH GPAAGIHLLC LADAPSATPA SPLTETYETA CASTPAFREC GAVALLSGDV
ATAVRTFAVS GGLPVPPGET ATADAVSAAW AERFARALAP LRADASQAEP SRTVAAALPQ
TSRLLDELGL ARATPASLMA RWAAATEQGQ GVGGLVEVVL GAGRRGPVGA ELVHDGPHLL
IEGPAGSGRT ELLRSVAASL AAAARPDRLG LVLLDGAGGE RGDGLRPCTD LPHVSAHLVA
SDPLRMREFA QALGAELRRR AELLDGVPFA EWHARREAGD RMVAPRRPTS GELRGDLEPQ
RTGTLRLRSA AFRTEPAAGP SPLPRLVVLV DDLDALVSPG LGNMGRPAAG SVVRALEAVA
RDGVRLGVHL VATSARPDRT ADTELARLTA LRVELDAPDQ PGPGRGRLLR ADGSAVPFQG
GRVTGRIPRT ATLRPTVVPV EWERMGDPPA RRPVRELGNG PTDLALLASA LDRAAHLVSA
IPVLFPAAP
//
