ID A0A0G3URI5_9ACTN Unreviewed; 1115 AA.
AC A0A0G3URI5;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:AKL68266.1};
GN ORFNames=M444_25765 {ECO:0000313|EMBL:AKL68266.1};
OS Streptomyces sp. Mg1.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=465541 {ECO:0000313|EMBL:AKL68266.1, ECO:0000313|Proteomes:UP000035653};
RN [1] {ECO:0000313|EMBL:AKL68266.1, ECO:0000313|Proteomes:UP000035653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mg1 {ECO:0000313|EMBL:AKL68266.1,
RC ECO:0000313|Proteomes:UP000035653};
RX PubMed=23908282;
RA Hoefler B.C., Konganti K., Straight P.D.;
RT "De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using PacBio
RT Single-Molecule Sequencing.";
RL Genome Announc. 1:e00535-13(2013).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP011664; AKL68266.1; -; Genomic_DNA.
DR RefSeq; WP_037798270.1; NZ_CP011664.1.
DR AlphaFoldDB; A0A0G3URI5; -.
DR KEGG; strm:M444_25765; -.
DR PATRIC; fig|465541.12.peg.5441; -.
DR OrthoDB; 134712at2; -.
DR Proteomes; UP000035653; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000035653};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 259..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1115 AA; 117321 MW; 6956C759B9145229 CRC64;
MVCIRVLGSF AAERDGETVP LGGHRQRSVL ALLVSARGRV VSVDRMIEEL WQGAAPARAV
ASLQAYVSNL RRLLEPGRAP RAAARLLVSA PPGYALRLPE DAVDAWRFER LLGEARELLD
RAPDRARRLL REALALWQGP AYAETADEPW SHAEITRLDE LRLAARELDL AAGLRVGDSA
GVVARAALLT RDEPLREEGW RLHALALWAA GRQADALSAL RRARAVLAEE AGLDPGAALV
ALERAILAQD DRVLRRATAA PGPAEVPAAE PAAAVPAPPR AQPSDGTPEA APAPFVGREA
ELALLTGAAD RARAAGPGIA LVSGEAGLGK SALLHRFRDR LRSEGWLVAV GHNADAEGAP
PAWAWAEALR TVAAAVPPGS GAAAAVAPLL SDADEPSRAA GDTAAGRFRM HRAVWQWLAE
AARERPVCVV LDDLHWADGE TLALLAGAAE PPAGTPLLVV GAFRPDEVPG RLADTLALLA
RRSPTRVALP GLPEAAVAEV VRALGGPEAD PATVAALAER TGGNPFYVRE SARLLGSEGA
LVALSDVPEG VRDVLRRRLG RLPDAVVSAL RLAAVAGREC GVEVLVGAAD AGEDAVLDAL
EAGLVAGLLV EPGPGRVRFA HALVRDTLLA DLSRLRAARM HGRIGQSLER LAPDDVSGLA
HHFVRAASSA TAAKAVDYCV RAADLADRRF AHDTAAALLV EAVACFERTP VPPGAAGDRD
GERVGLLGRL VRAQVRAGAV MAARETRGRA IECAVGTGRE SLLISAFTAW TEPSPWQTRP
YGAVDRPVVA LLERLLERPG LEPAVRCRLL GAYAAELSDA RIPRVRAAAR EAVALAEGLG
DPELRAAALV TLLRELDPDL EGPERAGLGR ELERLGAAHE LPAHRWFGQF TRATAAAAAG
DAAGARGLLG EAAEFSRSYR MPEASAVSDC VTATLAHVEG RPAEAERLYA RAAEAMARQG
SPHAQGYLSV AVATLRASEG QLARTLPAAR EAYERYGPAV GDLLAVALAE AGEADEARAV
LERCGPLRPD YFFRVFGTFR AMTLVALGER RGAPELYAEL LPYRDAPPPA AGFTLATRPV
AHTLGELAVL LGRESEAAAH FEAAARITAR WRDPA
//
