ID   A0A0G3W8U6_9CLOT        Unreviewed;       490 AA.
AC   A0A0G3W8U6;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:AKL94332.1};
GN   ORFNames=CACET_c08230 {ECO:0000313|EMBL:AKL94332.1};
OS   Clostridium aceticum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=84022 {ECO:0000313|EMBL:AKL94332.1, ECO:0000313|Proteomes:UP000035704};
RN   [1] {ECO:0000313|EMBL:AKL94332.1, ECO:0000313|Proteomes:UP000035704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1496 {ECO:0000313|EMBL:AKL94332.1,
RC   ECO:0000313|Proteomes:UP000035704};
RA   Poehlein A., Schiel-Bengelsdorf B., Gottschalk G., Duerre P., Daniel R.;
RT   "Genome sequence of Clostridium aceticum DSM 1496.";
RL   Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP009687; AKL94332.1; -; Genomic_DNA.
DR   RefSeq; WP_048407527.1; NZ_CP009687.1.
DR   AlphaFoldDB; A0A0G3W8U6; -.
DR   STRING; 84022.CACET_c08230; -.
DR   KEGG; cace:CACET_c08230; -.
DR   PATRIC; fig|84022.6.peg.839; -.
DR   OrthoDB; 357309at2; -.
DR   Proteomes; UP000035704; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035704};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          66..112
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
FT   COILED          237..290
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          314..348
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   490 AA;  56544 MW;  11887AF28F501CCE CRC64;
     MREIVHNLKD ITDSRELLES KPPAFTILFI YILIALLTIA VVWSYIGEMD VVVKADGVVR
     PNQRISTINN MVGGKVKEVY LEGGKQVTKG DILYIIDDAD LQIKKEFLQE EINRKTIELE
     NVNKLKRSIL EDTNYFSSAK KEEELYYYKY LKFQADKNHS RENVNLIIAN IENTKDTTTN
     LQTLSNAIKT NINLFEDLEN EYYAKYIDYN LKLKGLKDTL YQRQKEYQIQ EKMYQAEAVS
     KVDYEKAEDA LEQAELELEK FQNSIRLDLK LNLEENQRRL RELKIQLQQT APGTTEALEA
     YPNIAVDHFK NENLISVNDH IKNLQVEIRQ LENNLQTVKL DIESSIVRTP IDGYINIIQD
     INKGDSIQGG TVATIIPDND TNYKVQIYAP NEEIANIKVG DKVKYNFLAL PYKEYGELTG
     KITKIAIDTK VTNEGNTSYY LVEADIKNRP LISYKGEEAE IKVGMVCEVR VVTKTKKILH
     HLLEKIDLRL
//