ID A0A0G3WC02_9CLOT Unreviewed; 774 AA.
AC A0A0G3WC02;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=DNA translocase FtsK {ECO:0000313|EMBL:AKL95420.1};
GN Name=ftsK1 {ECO:0000313|EMBL:AKL95420.1};
GN ORFNames=CACET_c19720 {ECO:0000313|EMBL:AKL95420.1};
OS Clostridium aceticum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=84022 {ECO:0000313|EMBL:AKL95420.1, ECO:0000313|Proteomes:UP000035704};
RN [1] {ECO:0000313|EMBL:AKL95420.1, ECO:0000313|Proteomes:UP000035704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1496 {ECO:0000313|EMBL:AKL95420.1,
RC ECO:0000313|Proteomes:UP000035704};
RA Poehlein A., Schiel-Bengelsdorf B., Gottschalk G., Duerre P., Daniel R.;
RT "Genome sequence of Clostridium aceticum DSM 1496.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; CP009687; AKL95420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3WC02; -.
DR STRING; 84022.CACET_c19720; -.
DR KEGG; cace:CACET_c19720; -.
DR PATRIC; fig|84022.6.peg.1969; -.
DR Proteomes; UP000035704; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000035704};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 441..628
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 749..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 458..465
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 774 AA; 86272 MW; 95886EB30B87F82C CRC64;
MFNRAKNQVK TTDIMLQYML YILREVIRLS RKRKKGKDAF ISLKEEFNNE IYGIFTIALG
LILLTALQSN SGGKVGEGLK YLLMGLFSNI ALILPYVMVL LGVLIFINKP FWKELKGRLF
FILTFLCLLV FRTLLELSLI EALTEASFYE AIKTMFAKGT EGIGGGAVGT AITYWLVSLF
GQIGTYIIII TLSLISIIIY TKISLLEFTI KLKDYVGKIF YSAGQLIYGF KVTPQSKKRK
LKEKEDPLEN QLTAVESNVE EKIKILDYTV VSKEDLQENP LPEKQENEPP ILEMETYSSD
EHIQYEIPSI DLLDEINHLP NKDDKRKIVS KAKTLEETLK NFGVQAKVLQ VSKGPAITRY
ELQPSIGVKV SKIVNLSDDI ALNLAAPAIR IEAPIPGKAA IGIEIPNEDV TIVTLREIID
SESYQSLQSS LPFALGKDIS GSPFITDIGK MPHLLIAGAT GSGKSVCINT LILSILYKST
PEEVRLLMID PKVVELNHYN GIPHLLIPVV TDAKKATSAL NWAVQEMTQR YKTFSENSVK
DIAGYNKKFQ DNKLPYIIII IDELADLMLV AANEVEDSIC RLAQMARAAG LHLIIATQRP
SVDVITGVIK ANIPSRIAFS VASQTDSRTI LDMGGAEKLL GKGDMLFYPI GASKPMRIQG
AFVSEKEVEE VVNFIKNQVE RPSYEAEIIE KIDQNNILQD NTDSDELFEE ALKIVIQSQQ
ASISMLQRRL KIGYNRAARL IDEMEAKGMV GPHEGSKPRQ VLAGKEVLQQ ESNC
//
