ID A0A0G3WGU2_9CLOT Unreviewed; 491 AA.
AC A0A0G3WGU2;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=DNA polymerase III subunit alpha {ECO:0000313|EMBL:AKL96679.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:AKL96679.1};
GN Name=dnaE1 {ECO:0000313|EMBL:AKL96679.1};
GN ORFNames=CACET_c32350 {ECO:0000313|EMBL:AKL96679.1};
OS Clostridium aceticum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=84022 {ECO:0000313|EMBL:AKL96679.1, ECO:0000313|Proteomes:UP000035704};
RN [1] {ECO:0000313|EMBL:AKL96679.1, ECO:0000313|Proteomes:UP000035704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1496 {ECO:0000313|EMBL:AKL96679.1,
RC ECO:0000313|Proteomes:UP000035704};
RA Poehlein A., Schiel-Bengelsdorf B., Gottschalk G., Duerre P., Daniel R.;
RT "Genome sequence of Clostridium aceticum DSM 1496.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009687; AKL96679.1; -; Genomic_DNA.
DR RefSeq; WP_052661295.1; NZ_JYHU01000005.1.
DR AlphaFoldDB; A0A0G3WGU2; -.
DR STRING; 84022.CACET_c32350; -.
DR KEGG; cace:CACET_c32350; -.
DR PATRIC; fig|84022.6.peg.3307; -.
DR OrthoDB; 9803237at2; -.
DR Proteomes; UP000035704; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd04485; DnaE_OBF; 1.
DR Gene3D; 1.10.150.870; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR040982; DNA_pol3_finger.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR InterPro; IPR029460; DNAPol_HHH.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004365; NA-bd_OB_tRNA.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR Pfam; PF17657; DNA_pol3_finger; 1.
DR Pfam; PF14579; HHH_6; 1.
DR Pfam; PF01336; tRNA_anti-codon; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:AKL96679.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035704};
KW Transferase {ECO:0000313|EMBL:AKL96679.1}.
FT DOMAIN 12..52
FT /note="DNA polymerase III alpha subunit finger"
FT /evidence="ECO:0000259|Pfam:PF17657"
FT DOMAIN 141..230
FT /note="DNA polymerase helix-hairpin-helix motif"
FT /evidence="ECO:0000259|Pfam:PF14579"
FT DOMAIN 345..413
FT /note="OB"
FT /evidence="ECO:0000259|Pfam:PF01336"
SQ SEQUENCE 491 AA; 56138 MW; 7C3A9553F5228DD4 CRC64;
MEITSKSYLS LLRVVRDLAG YSYSRSDLVR RAMGKKKRDV MEEERQYFIY GKLDKEGNIE
IPGCIRNGVP EEIANKIYDD MIDFANYAFN KSHAAAYAIL GYQTAYLKTY YPVEFMAALL
TSVMGNTPKV VQYIQDCKRM GIEVLPPDIN KSYSTFTVEG EKIRFGLAAV KNVGVNMIQT
MVQARDEKGK FISFSDFCQK VDAKDLNKRA VESLIKCGAF DSLKIYRAQL MGVYENLLDS
INQDKKRKIQ GQLGLFDMTG DATISFKKDP LPNIKEFQDK IRLNMEKDVL GLYISGHPLA
ELQQELKYFT SINSSNINEI MENPQETEHK DGEKIIVGGM ILEKITKTTR NNKLMAFITL
EDLLGTMECI VFPNVLNQHA NLLQEGNLVI IEGTLSLKDE ESPKILTNTI RPLAKLETQK
LYLKIREKSD MVLVHEAKNI LRKYHGSVPL YVYIENENKV FRADRDLWVK LNDDLIKELS
QIFGEESVKI K
//
