ID A0A0G4AW28_9BACT Unreviewed; 301 AA.
AC A0A0G4AW28;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Gnd, 6-phosphogluconate dehydrogenase, decarboxylating {ECO:0000313|EMBL:AKM79936.1};
DE EC=1.1.1.44 {ECO:0000313|EMBL:AKM79936.1};
GN ORFNames=UW38_C0001G0066 {ECO:0000313|EMBL:AKM79936.1};
OS Candidatus Saccharibacteria bacterium GW2011_GWC2_44_17.
OC Bacteria; Candidatus Saccharibacteria.
OX NCBI_TaxID=1619070 {ECO:0000313|EMBL:AKM79936.1, ECO:0000313|Proteomes:UP000035655};
RN [1] {ECO:0000313|EMBL:AKM79936.1, ECO:0000313|Proteomes:UP000035655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; CP011211; AKM79936.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4AW28; -.
DR STRING; 1619070.UW38_C0001G0066; -.
DR KEGG; sbag:UW38_C0001G0066; -.
DR PATRIC; fig|1619070.4.peg.61; -.
DR Proteomes; UP000035655; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Oxidoreductase {ECO:0000313|EMBL:AKM79936.1}.
FT DOMAIN 168..301
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
FT ACT_SITE 172
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 301 AA; 32172 MW; DA2AE43E5B321F33 CRC64;
MKIAISGLGR MGGQIAKKLH DDGHDVVAHN RSAGKVDEAK AWGATAAYDK QSVVDAFADQ
PVVLWIMVPA DVIESELDEW LEILPSGSVI IDGGNSDYRG DQARADKVSA RGSRLLDIGT
SGGVWGLENG FSMMVGGDPQ SYQTVVPALE TLAAPRGGHQ FFGAVGSGHY VKMVHNAIEY
GMMQSLAEGY RMLKEGPYKE IDLAAAGDIW QQSSVVTSWL NDLTRQALHE NPTMEGISGV
VAESGEARWT LETADELGIP MPAIQAAFDV RLASQQGDVD FSTQLLAAMR AKFGGHDING
K
//
