ID A0A0G4EIV2_VITBC Unreviewed; 1290 AA.
AC A0A0G4EIV2;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN ORFNames=Vbra_7604 {ECO:0000313|EMBL:CEL96624.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEL96624.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEL96624.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
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DR EMBL; CDMY01000243; CEL96624.1; -; Genomic_DNA.
DR STRING; 1169540.A0A0G4EIV2; -.
DR VEuPathDB; CryptoDB:Vbra_7604; -.
DR InParanoid; A0A0G4EIV2; -.
DR OrthoDB; 6297at2759; -.
DR PhylomeDB; A0A0G4EIV2; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17748; BRCT_DNA_ligase_like; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 2.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254}.
FT DOMAIN 484..554
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1146..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..233
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..386
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..610
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1222
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1290 AA; 139030 MW; 5945BC0F7F531A13 CRC64;
MAPPKKKKDD EKGKEKGLQD IRGFFGSGGI KKSTSPSPHQ SQQQESSPPV AAAAAAAAAA
AAPAPAKEEE EGVGGDDVID LEDEPEAKAS GKKRKGVDST PDKQKGKKGG GGGGAAGKGD
GDEEDEESDV RARRKKKPRR QLDLDDEEEE GSSRKLPERV AKSRGRERAV EQIDLDLTDE
EGGGAAAAAA AAAGGKASGK KGKGKGKRKK LDESDEDEAY VPSNGDDQEG DGDGDGGGEH
FGAMDKFVKR GDEAKKLHEA QKAAAARGKP QPSPSAPSRE EVSPDAFFGS AAAAAGKKDK
DKGKRQAGKP WLDRPKDFQS DAPDVDWKAL VKLKKNKKGE DEDGDDEDFE MAEAEDNDED
EDMKDLADED ENGDVPIGVD DDEEEEEPAK PLKKPKKSQS SPKPSAKKPP PPPPAPAKAK
KEPEKNKKIE DEEDDDTEKD EEPPAEEPKK KASPKKRVIP ASFAKPKPKA KAKPKAKAAA
PQPTASQPLA GKGFVFTGEL ASMSRTVAED RVRSLGGQVQ SAVSGNTHYL VLGSHLDDGR
DVKETSKYKK YLSIEKDRKD PSSKGYSRIK NKPPIQVIEE EEFLKLAPDI ADAPDDENEN
ENEEAEEMEV EEPDHHQQQQ EGGDDQEMTD AAGGGVPSGP RRPAKELWCE KYRPKSADEM
VGNHAQVTKL TEWLTDWHDV CIKGEKKTAA KKGNKDENIN ARACLISGPP GVGKTTAAHL
VVKECGYIPM EFNASDDRGK KIIETLGTGL GSNRLIDGYG SGAHSSMLGV TAGKGQQDMK
KACLIMDEVD GLGAGDRGGS QALIRMIKKS HIPIICICND RMSQKMRSLG NSCLDLRFYR
PQKQAVAKRM VEICAKEGMH IEPNSAQLLC EESHNDLRQI LNTLQVMRVE RRNVPFKKMR
DHVNSNEMKD QQVLLSTFEV AKLLLTPDGG RLPLWKRLDA FFVDYSLMPL LIQENYLQPF
TTVPARNEDP NSLKRVCQAA GCMVNADICE RQIRTNNNWS LLNALGILSA VAPGYFCNGT
IKWPQFPSWL GKNSTRTKNR RLLNELHAHL MLHTSGSARS MRLTNYTDIL FDRAMRPLRK
IEDNTEAATE CIEFLDAYGL TKDHLAEHLP SLRLPTQDDT YKMLDAKKKG VLTRLYNQKV
HKRTPMALFG GKKGGGAAKK AAAGGGGGGG GAGAGGGADE ADGGLEGAGV QKDAAPAEED
DDNGEGGSAD KEEEEEEEEE EGTMGGMIKQ TRGEKGLLAK AAKAKAKGGG GGARGKGKAK
AASGKGKAKA KGKAKDKPPG QTLHNFFPKK
//
