ID A0A0G4EQC3_VITBC Unreviewed; 6152 AA.
AC A0A0G4EQC3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=HECT-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012485};
DE EC=2.3.2.26 {ECO:0000256|ARBA:ARBA00012485};
GN ORFNames=Vbra_20681 {ECO:0000313|EMBL:CEL99629.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEL99629.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEL99629.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.26; Evidence={ECO:0000256|ARBA:ARBA00000885};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the UPL family. TOM1/PTR1 subfamily.
CC {ECO:0000256|ARBA:ARBA00034494}.
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DR EMBL; CDMY01000285; CEL99629.1; -; Genomic_DNA.
DR STRING; 1169540.A0A0G4EQC3; -.
DR VEuPathDB; CryptoDB:Vbra_20681; -.
DR InParanoid; A0A0G4EQC3; -.
DR OMA; ECSANER; -.
DR OrthoDB; 164548at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd00078; HECTc; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR010309; E3_Ub_ligase_DUF908.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR11254:SF446; HECT-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF06012; DUF908; 1.
DR Pfam; PF06025; DUF913; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF00627; UBA; 1.
DR Pfam; PF14377; UBM; 4.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 1626..1667
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 5817..6152
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 239..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1448..1501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1542..1561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1604..1626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1711..1829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1879..1910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1987..2034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2122..2159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2197..2271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2422..2484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2519..2752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2780..2812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2943..2969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3028..3094
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3131..3222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3285..3324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3351..3522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3696..3727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3758..3814
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3832..4152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4211..4470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4493..4553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4605..4628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4894..4934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4994..5017
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5068..5182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5322..5341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5383..5554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5590..5626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5658..5678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1477..1495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1713..1730
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1748..1767
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1807..1821
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2128..2142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2252..2266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2422..2437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2461..2484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2519..2542
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2581..2634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2641..2663
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2672..2686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2780..2799
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3055..3084
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3135..3181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3359..3382
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3397..3428
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3429..3445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3446..3460
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3471..3517
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3911..3936
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3950..3964
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3997..4017
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4069..4108
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4109..4129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4219..4235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4290..4304
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4493..4528
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4915..4932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5068..5098
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5147..5171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5419..5439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5451..5476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5493..5519
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5597..5611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 6119
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 6152 AA; 652161 MW; 7108E7E117DFB29F CRC64;
MRIEYNQNAL HALAAASLSE PQRVVIETLV TSPLDQLANH LEGFQWCFEK GNLEHWACVI
NRFDSCLRAF VRRNNLWTPA SSLYDGEPDV DGEVTEALAH QILKATHIIL ENCTNKHHFN
SLEYATAVLD SFNLDVVYAA LRLLTSYYYS IKRSRKSSTD ALCHDELFHR LTVLCESPLG
DVYFPSSPAP SLTSASTAVK SDADDMERTD MRSLCTPGAP VPAMSGGFFE VEAYIHKGHN
ARGPRPGPGP GAAGPAPACG GAAASSAGAV GGGGSGAVGG GARLIRTESI RIPVSELKSS
SGDRLHEEES DLRRLVDTYD IAPNQIPTLR HKIRIVRAME ADHMRQKLVA IRLAAMNCFV
SFSPNAFFGY LYGNPSLLVE DKQNYRTVLS LMGIASPYGL FPSLLRRILR HPYVAEPLFP
PLDPVAEDGD QPGPSSPLAA PPQPSPAIPM SDDDQGAAHG GLSLRPYSSS EDGAHYLVIQ
AALQLYSSVL QTSQTVQGSM STGVLCAVLD FLRSRDLHHI SPMLYATRLL EHCMQYSVQA
STLLMRECSA NERLIERIRW EVARVKELVD SPQASDAILH QTNATPADKA AYWQGKLLHL
NRCSLLKALM RTLKTLLEVG EGNPAAVGGL QSLLEGPFLP TVKDVFTCGE KMSLGSVGGA
MQLLGFVIGE DPTAIPSLIE KGLLSTLLDS INERTLCSDE VLGAYPTILA SIFLHNSGEQ
AMAQREYKPV GFTIDQISNK DLTLHFQTNE IASMLGASLE EITRNQPNSR RPIVNFCVAL
LRKMKEDAMK LPLWKPFNAE AARASPPPKP TELAYITNPP LPPDDYLPDR LHNLGRLLQA
FLSSTENAKL FVESSGLPLL MELCSLPALP SNFLQVTNGH SLPQIFSVGS TAMRISGQAW
AAILHPQLLS GAKRAVSDIT DTLKADQCGD EPIEWSADMT DDSTALFRLL QGIAKVDALL
WQAMTIYGGT SQSFQTSTPN SWAYLAAIAK EIVPVVKPLM REVYRQTPPG GCKPYPHPQL
EPLDPSTLLS FKFHAHDRTA GRLRGIQVDR TNLPSHMPIT LHTDYTAQAA DAFSIPNPAF
EPDGMATLPG PPASVAPDAL MSDGTSAALS PAPSSTSLPQ GDKEAPTYFK TSTPRAVVLE
AARTMLHTVR HFLTTVSRMA NYVQQRSRTR AATVPTPAQR AAALTLAQLG VDLLSDVPLA
PPPSIEVDRC RDHLYDKITP EEAMAALTPK DEDVTMADAH AETDGGGGKE VKESREMSLQ
IQGMTPVQTA RYLSDVVEFL SKLHVDDRNH GHINTLSLDY FYKLHGMKYV YRALAYEFGV
LHSVAVSFLS LDAQAACELT NANKDAVWPL WVDRMTELVK KEDIDTAAAV TAEADITERQ
RLALATLSKC VQSCTTYLER LTSWKRFSTP QITQFLHKGC KRPSAAQRGG PAAAGAAATT
SAAQGSAAEG AGSSAAQAGG TSTAAAGGEG APSVGHPPSQ QAGTAMDTTT GGGDSAQDAA
VKERDAELAT FDALRFGETL QIEAVAHLLP WWRLFDATQY GKPSSSGDAS TTAHTRATST
PVVSTTSQPM LLYAVSVYPA KAMASILRIF THLLDTQTDQ RRSANAPWLT APGGGGPGGA
ERPRSQVDPG AVQTLVDMGF SRVLAEQALM STGTSSLEVA ADWILQHQHL EGPVAARAAH
EAANAGATAL QAAPEETQLL EGLIRGLVGS LPAPAPVPGP PPPPPAQPGA PADTTADVPM
APAGETADSD GQGQQMDSAQ EGPPSPSRRS GRRSRARGGR RGRNASPMSR TPRAPQGDPS
PPASETPSPA TASIQPTRRQ ESQSTLEKHW PEEEVKSVLN NLKSDFFYRL INVGCRVPQC
SVQVTDACLR SVNFNLDFGR RPEQSGAPSG GDAGPGIDTH SEVPPSGVPS RRHVGIFGFL
AGDHPDRPRR HQDNPAMNCE IVMDEILRRL QSCVEAFPSS SCPVYLLPIP DQPPGLPGSL
VDMSHQATPR GTPFSSPPPS PSPMYAGEVT DEERGGISPA GLNEGGGKDT TERQKVRAAA
QRFHEDLQCI LHLMANMLHR RSPARKALKS LVTSPLEGLY KLLQNFCEAH GQADELNPNR
LREKGLQPFP ALVPNPPLPL PAFALATPPS KTDTQSAPPH TRTAAAAPSR GSGPHECLTA
PDAGRPPAWF ASGYVCLSLF IKDYELWDLT DVFSIQPDRP LQPPTDDDKP APQQGTAAAA
AGEQPQGQGG STDVKAGEAA AATADGEATD QPVPMDTTTA PAQPADGTKK TSVLPVDLQK
GLVKVCLDTL HHFPGLDGNL AMAVLQLLVH LTSVHHNAVA MVNYSPRGLA ALASRWGGAA
KDTKASHGLS LFTPQQDKDG VNLRMGGLDL GGGLGVVFRI PKTARFNGLL AVVQTLVQRA
VEDYATLQSQ MEAAIVSLFT SQSQQGQRNS NGQAGGPGAG NGSRAGRAQQ GAAGQQAGGA
AGNRSEGQPS PTEESPTHAP QPTMTMEEVI TQSFPWIRRN PQAFREALSV SCAVLVPERR
KKEATADKDK DKQQKDEAGG QDSKEGGPSS EAAQPQPPPD VDMAASQQDG QPPADRPADG
DTSQAQDSQQ VVPPTVPVAT NVDQTQSQQP VQDGAQPPAP SQAGESQQAQ PPASSAGGGD
GGPDEDEEID DDEDEDEDGI AIDGEGDFSP SPRRPVGDDE DPPDTEPVRL QLLSTKERQQ
NKENMKLKKI AFTGQGQALA GSIPSSPPQS PAPLKPQPLP RTATAGEGPR GSAWSAVSTL
CDYLSVFVNL QASCSFTPFT PLQQKKSSTD SSPRAAESAQ QEGEQRPAGM SVEAGGLTLD
SYRERPMWKL PVGKKGEKPE YPYALPPDSL VYLLNGLLSS YSNCLALLIK SAHSQGGNVS
PLRKSIKEGT AIWFSTLPPW PFTSCATATS SAGTPKPILS VLMRRVLPAL ISLNTAETVH
GWRQSVMRSR QPANQPGGLT NGDNGDQTKS TMAVSVLPVK QTPPCRILMQ FVGVLTTVAQ
KNPEIRKKVT NEVTALLKLL AIVATADTHP SGLPAPPNSS TVRPHTPSKP RKKSAPPSEA
PRDDKEKDSR AEPERKERVR HSRGGTADTA TMETPSLVPE LIPSLPSFFM TAVFVLAELL
HKLLSMPAVP SPPVGGNARN NNPNTTTTTG NAASVAPGGP SGQEQQQQQQ PAAQGGTPAS
QDQPAAAAAA GGLEPPSIPP PTSDVAEQGA AHPGATGTAA SPACLPSPLP PIQYIGGLCA
SDCPAVRESL CKLLNHIDLC REDSHTVCEK VARCIEILTR DSAFHASGEG PADDHPSSGG
LSRGEASPRE APRPPRGRRR RRDRRYEMDL DIDHESPQAA NGQNGLLEVE VEIDREPISG
FGDDDDDEGL SDGEDEDAPS EATERQEEPL PHEADEHEDN DVDEESREDE DLDEDEDEDD
DLDDEDDDEV RIRQPAPVGV RDIDEEGEGP MDEDEEEDDI GPRGLIDRDD VHDEDEEPMV
GDIDEDRPED EEEDEDDDEE VSRHEDEYGE AEFDERENDL GEVDRDLMQG GGRDMDLEDI
LFGGGGPEMF DHLNDEFRLS RVAMSRYARP SSIRRMIEGI SGGPLGLEME IEYLSDMPQG
SAAGGAAPAG PQAGLAVSGD LALPSEHPLL ARNVAAAQPA AAGAAAAGVR IRDDRPLMFR
GGDPLAPPVV PSPYGPYGDM GRGLQYERYA RYEAGVPGGG GPGAAGRARA GAQGEAGRAA
AGGPAAGVSV DAATTETGVR QVMSDMSANV RSLLRTIPVP APERPQPPVR PAARAPQWAR
RASRRDVRDV VGRPPPPDVP DRGQQLSEDI HEGVQRARYS RYGLRGLAGE PRMRGEAAAE
GGAPSGAGRQ AAGAPGGDQA RGVPPPEGDD DGASSGVGER DGSAEGRNGG SSPSAAGEAL
AAGVRQLNLA EGGPDEREER PGQPGEEGRI PDEDFVMVGE PPELLQERQQ QEHPAAQSQP
TAAAPEQPQA PPAAAAAAAA GGGGAGAAAE QPDMTMSIDG LVSSLTRSMQ SAAPPPPASA
AQEQPPQVRL DLNFVQQALA RVREHSPTAA GQAGRSTGEG EAQQDASAVP PPFAPPDVTA
PHPPPPAAAP APAAPASQPP PPASEQRDQP PQEAPQQGEE QSQPPAESQE AAGESPAGGE
GEDDAHLDEP LPFQSDLLSA IARSLDVSER FVLSCAGVDF QFLTELPDEF RREILQTQLD
TIDRQDIIRR RDQRRQRQRQ QPQAQPPQQA GGASPSAAAQ GGAAEGEEQP PPSTQEAPAE
AQQGEPPAAP ADLGPPIPME EVAPVAPSEQ PAEAAPPPQP PTGDGLEVPQ EGAPPAEPQQ
DGGEQGAQPM DIEGVAGSVV HPPAATAPAA PSEAPAAAAE AAQPPQPSRP PAISTDETMD
QAEAGGQRIQ VPMMTPPALH ESMITPTAPR RPSMAILEDE SGAASGEGTG QEGATARREG
GGDEEVLGEG PAGEGRAGGE AAAAAEGGMG DINEEVLAEL PPDIRAEIME QMRAEREQER
QRERAEREAR AARGGEGQGG EREGRPAGER PAGGGARGGA NGSRGGALLG GPGDMDNATF
IATLPEDLRR EVLLSATPEF LNTLPPEIMA EAQLLQERHN NQRMWAGRHG GRGEGGGAER
PPSQRRVPAG MMQGPPILPR HLAEWAPGSG MGLTDFLSDL MALGGGPIGS RVELRMPDGP
PRHYAIRRAP GAGGGPMMAA LRAGSRGVAR HRAPPPFIRQ GGEGDVFTDL FGAGSRGGPL
MAVPPSGYAH RGGGPGGVGG AGDRHVFLMP TPDGRIIQLS SRELQAMGYD IGPGLLQGDG
RAGLGPPPPG GDPGAAVMYS CRDPPMEPWA VVALCRLLYM RRTLHENLLH RNFSNLVVAH
PQTRQTVLQL LTQMIWCGGY PSILHLQALN ANKHTDGRVR PFPPRRLYSP SDRMASATEP
LNHPSRNNHP SFETGPDAAA FVGALRGLAH MRSILNVHPG CAEFFATKVL HPSRYSAEDG
DPSQDGVLAH ELKRKRKKRD VQASAGPSGS GALVPRERFP AQEHPINVLL DLTSTTPFLC
SASHMDSLLQ AIHTLICGPY YDPQLPPPPA PAPAPAPAPA PAPAPAPAPA PAPAPPAPHA
ADGDQQQAGA AAADAAMDAA PAPAAPQEAA EGQQAPATGA AAPMEVEGDQ QQQQQQEGAA
AASQTPGPTA AGDTRTPGGD AQMADAEVGV GAGEAAVTKS LPDRIVDVVK PEAADALCRL
LCLPSTKPHA TMWLAVTDTN KKDNNLTRVA QIVGRLFRSD KHSEGVYASL LHNATDLVDA
LCYQVDCLEA SIRREHSLPE EDAGALTPSS AGYRTSVSFP SLSSSAREAQ PPTLAASASM
PLSLPVRARP MREGSDVDAP AHGGTFELQT TAFVRLVHTL QDVLGSPTPP EEPPMGIADN
DNGEPLPDHD GDGGNNDGGG ASDGNQQQQQ QQQQGSGEGG QPPADAPMDA APPSQSQSQS
QQQQPPASQA TVATPQVAGA RGTEEAPGQQ PTPTSDQAPP SQPPPGEAPS QPPPAGQPDA
AQPSSSAAAA AAAGGEGEGQ PAAASAAEAA PRDPLHSMRQ VRDFFDAAES RRLWYRLEKC
MSTVARAFPH LSNRPGDRRV TPTSSSARAN AVRNGPAGAA AGGGAGRGAG RGVANALFGG
PGPLGGLMAA GAGGAAGAAG AAGGAGEGGD RQGGQAPPPM VLNQLLPLLE AWLQVQFYGI
VVDSDLTSAV APDDDGGPLV ADRDTFLNDR HQELVRVCER HRRALNALIR QTPTLLSTTL
APLIRLAPSA VDFENKRHYF KNKIRQLRSD VRHETLRLNL RRHSVFMDSF HQLRMRTGEE
MKGKITVSFQ GEEGVDAGGL TREWFSILSR EMFNPGYALF SRTGAKAEFN HPNPLSHVNQ
DHLHFFKFIG RIIGKAIYES IHLDAYFTRS CYKHMLGRKP KAADSEALDP EFYKNLMNIL
KEPLDMLGLE LTFSTEVENF GAMMTVDLKE NGRNIPVNDE NKEEYVGLMC EYRMTEAIKP
QLDAFLSGFH EIIPAKLISI FDDKELELLI SGLPEIDLDD LRRNTEYTGY TEDSQVITWF
WKTLQTFDQN RLATFLQFVT GTSRVPLEGF TNLMGMRGPQ RFSIHRAFGE DRLPSAHTCF
NQLDLPEYSN EDQLKTKLIQ AIHEAREGFG FI
//
