ID A0A0G4EZZ0_VITBC Unreviewed; 1336 AA.
AC A0A0G4EZZ0;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=Vbra_14058 {ECO:0000313|EMBL:CEM04626.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEM04626.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEM04626.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR EMBL; CDMY01000354; CEM04626.1; -; Genomic_DNA.
DR STRING; 1169540.A0A0G4EZZ0; -.
DR VEuPathDB; CryptoDB:Vbra_14058; -.
DR InParanoid; A0A0G4EZZ0; -.
DR OrthoDB; 215129at2759; -.
DR PhylomeDB; A0A0G4EZZ0; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254}.
FT DOMAIN 142..322
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 357..549
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1059..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1205..1237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 981..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1014..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1059..1103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1159
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1336 AA; 145609 MW; 4E6D63C8CBE7BA53 CRC64;
MAAQWGRPYT SSQFADDDPI EDLPEMPSSS ASSYQQQQQP QRHLANPFGH IATRPNAHWS
KASSLTRASN TSTTRGQQQG HQGHRPGAAM SRYGQSSYGS SGPSAQAAAQ TSLVCVSQAL
PPRMSHIFPY SHFNVVQSEC FNDAFGSDSD LVVAAPTGSG KTGVLELTML RLIHTNQDQF
NGGVDVPKML YIAPIKALCS ERMQDWQHKF GELLGLTVFE VTGDTDDSTT SFMNNLYMAH
LLICTPEKWD FVSRKTPDII SHIRLVCIDE VHLLGSKRGP CLEAVVARHM IQAKPRLVAV
SATVPNLDDV ASWLGCGADP GATMRRFDAT YRPVPLQHIV YGYPPAKDNN GFLFERGLNQ
HVPELIRRHS SGRPCLVFCV TKKGCEQTAA AIRDSGLQLV QNDHHRHAAA QLASQLPESI
RKYVSAGVGV HNSGLKPEER RVIEDGFVQG TLRVLCTTTT LAQGVNLPAH LVIVKSTLAY
KGAGYVDYDD LEMLQMIGRA GRPQFDDKGV AVIMCPNNSK AKWERMVQGN VLLESSLASN
LIEYTNTEIH LRTIDSYETA KQWIRTTFLY VRAKRQPQKY EMRSPIDPAI DAKVNETIEQ
LHEVGMILVD EASGAISSTA LGSVMAKHSI KFETMKNFIQ IDPREVEANS PKVEKGLLEA
ISQATEFLDF PPKQDQRKPL RTLATNCRYP LKNQAIGDAH KKAFVMLQCA LEHTKTNQWE
LSAQFDQIRR LAERLSTVVE TVLTEKPYNG VALAEAIKVE RALKCKIWND SRDLQLTQLD
GIGDGFAAKL HGHRVSTLDQ LARCDSSKLS MMREGQLSLQ RLTEWSRTAA SIPRYEVTIE
VQQQGRTALV TLEPMDVMPS WQTVAGFEPQ RATYHLLLYS DERQLIFNRK IAVNAANYGQ
PLTFTAALPT PVGQSGCIFG QLICREYIGI DRAFSWPKGL TSSSLVQLEP TAQAKPKAKS
SKKRNNNDSK SAAGRPAKLQ RTLSPYQQQA AAAPGGTTGS GWITKKAPPK PKANIATQSM
NNTSTNTDFS GAAAAGGAGG GGIASGQGID SMATWRSLSR KHNMSSGSTG RLTPHDTPNA
MTTTASDQQP AEPPTQPSTA NIARVSPGVP RPLNRPSISP RFPRSGAGAG VSRPVPRPPP
VNRNPNAPVM MPPRPPAQPP FPHNVARPFV RPPPPTYGVA RPFVRPPPHR PVCAPAARPR
CVSVSASSRF GPPAPHQNHN APMHMSTTTT TTTTTSTRSS YAAYAMPQSY NPVMHQPAAS
QPFDPYDDDN TEMDTGIDTH THTADDMMTQ QPQPGVSGVG GGMGMGVGLG VGAEHQGGTA
DMAMSQCDQL FTDIWE
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