ID   A0A0G4GCP7_VITBC        Unreviewed;       333 AA.
AC   A0A0G4GCP7;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Steroid 5-alpha reductase C-terminal domain-containing protein {ECO:0000259|PROSITE:PS50244};
GN   ORFNames=Vbra_22141 {ECO:0000313|EMBL:CEM26918.1};
OS   Vitrella brassicaformis (strain CCMP3155).
OC   Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX   NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEM26918.1, ECO:0000313|Proteomes:UP000041254};
RN   [1] {ECO:0000313|EMBL:CEM26918.1, ECO:0000313|Proteomes:UP000041254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhu J., Qi W., Song R.;
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CDMY01000624; CEM26918.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G4GCP7; -.
DR   STRING; 1169540.A0A0G4GCP7; -.
DR   VEuPathDB; CryptoDB:Vbra_22141; -.
DR   InParanoid; A0A0G4GCP7; -.
DR   OMA; FQMLWVW; -.
DR   OrthoDB; 177757at2759; -.
DR   PhylomeDB; A0A0G4GCP7; -.
DR   Proteomes; UP000041254; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1630; -; 1.
DR   InterPro; IPR001104; 3-oxo-5_a-steroid_4-DH_C.
DR   InterPro; IPR010721; UstE-like.
DR   PANTHER; PTHR32251; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE; 1.
DR   PANTHER; PTHR32251:SF15; 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295); 1.
DR   Pfam; PF06966; DUF1295; 1.
DR   PROSITE; PS50244; S5A_REDUCTASE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000041254};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          145..227
FT                   /note="Steroid 5-alpha reductase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50244"
SQ   SEQUENCE   333 AA;  37862 MW;  8D6AE28508C36091 CRC64;
     MAAIEAFAFD THYFFLTFLV TCAVQYTCFA IAYGLQFDKI TDLSGASNFV INIIIPLILA
     NTYFERQVLV TVFIVVTRLY LAGFLFYRVL QRKSDTRFDT FRSNFLYYFG FWTGQILWCW
     GSTLNGIFVV SEKENPSLGP TDFIGIVLFA LGFICQVVSD VQKYIFRANP ANRGIPCTTG
     LWAYSRHPNY FGEMVIWWAI FLMSARAIHE STDTWGWATV VSPIWTMILL LFLSGIPYAE
     GANLKRYFEN PTSRPMIEAY QRDVSPVIPM PQVVYRNLPM IVKQVFLFEF PMYEYHYVPP
     DSTAAQAAAA NGGAGNPIEL SNTSAEREAL IQA
//