ID A0A0G4GJP6_VITBC Unreviewed; 394 AA.
AC A0A0G4GJP6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=Vbra_18040 {ECO:0000313|EMBL:CEM30163.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEM30163.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEM30163.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; CDMY01000688; CEM30163.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4GJP6; -.
DR STRING; 1169540.A0A0G4GJP6; -.
DR VEuPathDB; CryptoDB:Vbra_18040; -.
DR InParanoid; A0A0G4GJP6; -.
DR OMA; AYRNNEH; -.
DR OrthoDB; 3639304at2759; -.
DR PhylomeDB; A0A0G4GJP6; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254}.
FT DOMAIN 29..372
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 394 AA; 43242 MW; A5E3F09CD2A138E3 CRC64;
METINEGDAP ALLTGELNLT QHPNGLMEFV LNRPKVLNAL SVDQVACIGE YLWILDHKRG
KECQAILMRG EGQKAFCAGG DVRRMAEGEA AYSVRFFSRE YLMDYRTSQL KKPYVALWNG
IVMGGGVGIS VHGSYRIATE KTMLAMPEGN IGLFPDVGAS HALAPLKGFG LYLGLTGARL
NGADVLRHGL ATHFVPSESV ESLIQELREA PLGDCDVGAA HQAVKTLLAK YGKSLDEVAK
TLPPSVDQEA LSAVDQVMSP PSASLSEVMG RLRERIGSSQ GQIKDFLQKA ESAIRAKCPM
SCVVWHRLLK EVTKPDGSVI DLADCLRFDF ALAQAMTVHD SYNFREGVRA ALIDKDQQPK
WQPPTIEDME HDTQRIDMLF QCPQGERLDD VVKM
//
