ID A0A0G4GQI0_VITBC Unreviewed; 1068 AA.
AC A0A0G4GQI0;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Apple domain-containing protein {ECO:0000259|PROSITE:PS50948};
GN ORFNames=Vbra_18362 {ECO:0000313|EMBL:CEM32697.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEM32697.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEM32697.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CDMY01000759; CEM32697.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4GQI0; -.
DR STRING; 1169540.A0A0G4GQI0; -.
DR VEuPathDB; CryptoDB:Vbra_18362; -.
DR InParanoid; A0A0G4GQI0; -.
DR OrthoDB; 276532at2759; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd01100; APPLE_Factor_XI_like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 3.
DR Gene3D; 3.50.4.10; Hepatocyte Growth Factor; 1.
DR InterPro; IPR000177; Apple.
DR InterPro; IPR001360; Glyco_hydro_1.
DR InterPro; IPR018120; Glyco_hydro_1_AS.
DR InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR003609; Pan_app.
DR PANTHER; PTHR10353; GLYCOSYL HYDROLASE; 1.
DR PANTHER; PTHR10353:SF36; KLOTHO (MAMMALIAN AGING-ASSOCIATED PROTEIN) HOMOLOG; 1.
DR Pfam; PF00232; Glyco_hydro_1; 3.
DR Pfam; PF00024; PAN_1; 1.
DR PRINTS; PR00131; GLHYDRLASE1.
DR SMART; SM00223; APPLE; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 3.
DR PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
DR PROSITE; PS50948; PAN; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|RuleBase:RU004468};
KW Hydrolase {ECO:0000256|RuleBase:RU004468};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1068
FT /note="Apple domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005191031"
FT DOMAIN 324..399
FT /note="Apple"
FT /evidence="ECO:0000259|PROSITE:PS50948"
FT ACT_SITE 999
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10055"
SQ SEQUENCE 1068 AA; 118628 MW; 2497B23651E5199D CRC64;
MQPQLTFGFP FLLLASSPLA ALSFRPAAIS HQCHVDEALK GLVNKPWHKY DKALPPEENL
LAALTAAVEK GKKEGRKFLF GTSTVAFQVE GHSSGDGRHD SVWDAADKKA GRKPSEGAGF
HDKFEQDIAK AKDMAFDAFH FSISWSRVMT KDNKPNHKGV SYYQRLVKAI KANGMEPIAT
LYHWDMPQGK DWRVKSTVDD FAAFAEVMYT GLPSVNTWIT IHDPYAICHF GYHQGTIPPF
VRGGEGDVEK CARSLLLAHA RAVDVHRKKA PKDGGGKKIG FTLSLASDHP YAHPAGKGRR
LQETNYTTTE YLRALQEPSG EDACIEKGID FYGYDVFEVH AASPAECRVA CQGHDGCLFF
TYRADGPDAP EGINNCYLKT SDMGRTASEI GDVLMSGAAE CSQGGLQAEI LGKDDQGRDA
LDFQKQTFLD PIFRTSVSPL VSSGGGGWLT AEEKTLLADA KPDFVGIATY GTLNGASDQS
VWLRAIEHAP LGKALQQLQK EYNPKEILVT QMGLVNAMED YLPEKALLND QQRIWYYHMT
MFELAMAALH RGVRLGGMFA WSLVDVPKAA VQMSSGKVGL MSVSDDSKKE RKIKESGNWF
KHLIRAVHEC VKKGWSCNAA ADNLLLKPNG MAKAPNMPYE QGILPLLATA VQKVEGSGIA
KPFMWGTATA AYQVEGGWNK GGRAPSIWDE FTHAEKAHNG HTGDVACDFF HKYAGDMARM
KGSGFNAFRF SISWSRLMPH GKRNQAGVAF YKDVIKATKE NGMQPLVTLY HWDLPAGLDW
REKSVVDAYV KYADLVFSEF IDHVDDFITF NEPWVFCKLG YQLGIHAPGV KSTADDLKCG
HHVLLAHGKA VKLFRSKYQR KGKRIGITLN HEWRVPHNPS DPKDVTRTQG AIDSQLGWFA
DPIYLGDYPK TLKARWGKKM PVFTPAEKEL LKGSSDFFGL NMYTTLYESH EDGSSYERFS
VPIGPEAASI WLYPAPFGVA QLLKYVQNRY NPPSIIITEN GVSAVNEEYM PNPRKQKITL
KDSFRFGLQY VDFDAPERPR YMKESAKYLG TLIPSVRAQI DTCKLSTQ
//
