ID A0A0G4IMY8_PLABS Unreviewed; 4658 AA.
AC A0A0G4IMY8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=PBRA_005217 {ECO:0000313|EMBL:CEO96608.1};
OS Plasmodiophora brassicae (Clubroot disease agent).
OC Eukaryota; Sar; Rhizaria; Endomyxa; Phytomyxea; Plasmodiophorida;
OC Plasmodiophoridae; Plasmodiophora.
OX NCBI_TaxID=37360 {ECO:0000313|EMBL:CEO96608.1, ECO:0000313|Proteomes:UP000039324};
RN [1] {ECO:0000313|EMBL:CEO96608.1, ECO:0000313|Proteomes:UP000039324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3 {ECO:0000313|EMBL:CEO96608.1};
RA Chooi Y.-H.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CDSF01000068; CEO96608.1; -; Genomic_DNA.
DR STRING; 37360.A0A0G4IMY8; -.
DR EnsemblProtists; CEO96608; CEO96608; PBRA_005217.
DR OMA; ILKNDMQ; -.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000039324; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000039324}.
FT DOMAIN 1994..2130
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2627..2777
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2984..3210
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1076..1095
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3452..3514
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 32..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4658 AA; 522441 MW; 0D06D194168DF6B4 CRC64;
METEGASSAL PVDDDVNEAE ASDKVAPSIV LPASTSKRSS ITGPSTKPGG PSRTSVLGAP
GRSSGFSSIG PDDNLDASEQ IPDDEAIAWI WARIRLDGFQ PEMWRDEHSF IIADFLVSPS
ITRLTVVVDT DNHRVVLHTD SMPTGVPQLQ YFIKDNGKTL LSIADARDAV QYGIVSGPAL
DNIFAVMTNL YVPTFLNNSS WPASVRKDFS GQLHKFMANL TETVNHSKGS TILYMPDEDL
SDVEAAVADK DLIQRLESTL IHWTRQIKEV VTNQDTSQHV EESGPLEEIE FWRSRTVDLL
GIRRQLERPI VVDIVRVLQI VGSSYLRPFE TLKGMIQSGS DEANDNLRFL ETLHEPCNKL
KGAAPNQIPP LLVDILNLIR MIWTLSKFYN TQERLTGLLR KVSSQIIKQC TKAIDLNEIF
NGDVHASMVH LRESISCGVE WRRIYERTVE AVRRSSSSQA AWNFDPSSIF AQIEAFVQRC
RELLEVCEGQ VQFARKSSTE SHGKTPLPTF GGSRGAETEK ALHDIEDAFE KHIERLRGLD
YNILDVKATD WHDDYNFFKN GVKDLEVMMT NVISSAFDSV STVASGVELL EAFAILAKRV
SMKTILNRKI ADVFTMLKSE VLWIKRDFDR HHEAPPLPPC QPKYAGRALW AHGLAKRIAS
QRAIIDGAAC LANDTSREGR EARFAMEQVE SVLVAYQTQM YTEWVAEVEA LNEAQPLIER
LELPLLLRGG ADAPGEANVD GPAADDAGDA PAGASADRRS SKHLQANFDK ALLRLFDEVV
YWQQFQGSEF AIPYVAYEMS KLHDAQRVLY QNVMLVVREY NAVLDALSPD ERQLFADHMR
KVDRRINPGL TKLTWSKKHV KEFFVKICRE QCHEVQALIG QFHHQHQFIV ATCRKIAATG
LVVIEKSTVY TDVMFDEAQS RHRVRVQQGL AAMHAEIVAS MNKSYDIFRE APSDVQRAWA
AYIRRIDRQI EAALRHMVKK SLMELSKAIA GDAKNETQAL FKVDMVLDEG SGAQTSTVAF
RPNMSDLTNL VNDISRKLMN TVKVVPRLTD LLEYKRKKRN NVTVVDSQAP AALAAAGVAP
ASPRGPRPVA PGGLPGDSDL QNFYDAIAND EDVLKTFVTI IQGMRNVTTD INDLVAYWKD
AYKSTWDLDK DAYMRRYANT KRPLSSYDMD ITRYKSMQED VQSEDPSRSV RFIRIDCTQL
KASLVAHCLD WQARLTTLLH SNASSELQAL RDLIASTSLE LRREPKDLEQ LGASLNLLSK
MKKEAPVIES RFEPLDDMFR TLAKFGVVIT DEEKEQLDDL RPSWSQYLTT LKEVDVMLTQ
VKQSMKRGLE MSLDAFNEAV SENRRAFLAS DVFKAAADDG TGIDVALVLV DSWRKRVQES
RGAAAAMKPG LDIFGVAQPT YKDLEDTERD LAALQAIWEL TSAWHANWQS WKTAIFRQLN
PEEMDAQATD VQTRLLKLAK VMKKWPVWNA ARERIEHFRT MMPLIKDLKN PAMRERHWAE
LKEEVQDHQF DPHDDAFTLG KLFDLGIHQH AETINALSAI ASREYSIEQT LLEIEERWRT
MNVEVVPYKE RYRKVVSTDD LFQTLEDHHV SLSTMKNSPH YITFEEQINL WIRRLNDIAE
CIESVLVVQR QWMYLESIFV GSEDIRKQLP VESALFENVN GSWVEILDRW NATRNAQRCV
DEDGLLDRLN RMKATLEKIQ KSLDQYLEKK RQIFPRFYFL SDDDLLEVLG QTRDPTQVQR
HVKKCFAGIH RLEIQAKERG DPSTSSSGAG AGGARSWEVI GMVAEDGEKV RFLYGIATQG
PVEVWLIKVE KSMRETLRKH MQEAVATVQK SMSKRENWIR STIGQMLITS GQVAWTSECT
RALADPQKAR KALKQTRNRW YRYLERLTVL IRGDLSAIER LKLVALITIE VHARDVIERM
LKHGATAVDD FQWTSQLRFY YDRSEGDYGE CQVRQTNTSF AYGYEYQGNN GRLVVTPLTD
RCYLTLTTAL HLHLGGSPQG PAGTGKTETV KDLGKAMGNF VIVFNCSDAM DYKSLGTLYS
GLAQTGAWGC FDEFNRIRIE VLSVVAQQIA SIFTAVAEKR DYMMFEGVNI KLNRAVGIFI
TMNPGYAGRT ELPDNLKSLF RPVAMMVPDF ALIAEIMLQS EGLKDARVLA QKIVTLYNLM
EQQFSKQEHY DFGLRAVKSV LNRAGAIYRE SSDLPEDVVL VRALRDMNLP KFVADDAVLF
AGLMQDLFPS LEVPPPNTAA MEDSELSAEG LQPNASLIQK IVQLYESKRT RHGNMVVGEA
LSGKSTAWRI LAKTLSTMAA TSTDDRVRRV ESFVINPKTV DNNELYGSYD LNTREWSDGI
IAAVLRRCCS SENTNEKWVV LDGPVDTLWI ESMNTVLDDN KVLTLINGDR IALTPQISLL
FEVQNLAQAS PATVSRAGMV YLDKNGLGWA PFVTSWLAKK DPDQADLLRA LFDRFVEPLL
AFKASSGCRE LIPITAFNAV QSLTRLYDSL ATPSNGVDAA PVVSAAAAAA MSAKDKEAAV
NEFASSPRAR LIEQWFMFCV VWSVGAAVDE PGRLKIDEFL REAQASFPGL NTVYDYVVDA
NKKEWITWEE RVPNTWAPPP HVPMYSLVVP TVDTVRNAFI VSALLAQRHP VLLVGVTGTG
KTVLASSLLS AMEDADSKTM TMTMNFSSAT SSAVTQAMLE SRMEKRQRNS FGPANGRQRL
VVFIDDLNMP APDEFGTQPP NELLRQWIDY GGWYDRQRQT MKVIIDMQVL AAMGAPGGAR
TPISSRFQSK FNLVHMTFPS DAQIKRIFGT ILTAHLANFD EQVKPLAAVC TDATLDLYKH
VIEAFLPTPS RSHYIFNLRD MAKVTAGLLL ADHNLFDTRD NFIRLWAHEC MRVFQDRLVN
RDDRQAFKGL VAAQLDTLFA TSWESLFGTL DADPLFGTFL SEGSLDDQDS EPYQEMADRA
AVKAFVTEKL EFYNMFPGNA AMQLVLFDDA VEHVCRIFRI ISQPRGNALL IGVGGSGRQS
LTRLAAYIAE VPVKQIEISK SYRAADFRDD LKAVYQMAGV GQQRCVFLIT DTQLIHPSFI
EDLNSILSSG EIPNLFPPDE LATVLDAIRP QAAEAGVPSH TDDGLYAFFI NRVRQNVNVV
LCMSPVGATF RDRIRMYPAL VNNTSIDLFA EWPDRALREV AAKFLCDVDF GTTDESLPKR
LAGVFCTAHL EVQACAVRMA QELLRFTYVT PTNYLDLVSG YRKLLIEKRI QLGDAADKLR
NGLSKLDESK TQVAEMTVEL EEKRKIVAAK KMDCEKLLVE IVSQQRSADE QRKQVEIEAQ
KTSTEEKECQ SIAESAQADL DRALPALERA VSALEKLDKN AVTEIKSYTK PPPIVARVMS
AVMVVLGKEA SWATAKKELS DANFLMRLKT FDKDNISSAT LKKINKYTAV KDFTAEQVVK
KSVAAAALCD WVVAIEVYAM TFRTVAPKRA ALKDATSSLE IKQKQLKVMQ ERLARVKEQV
AALEQRYESS ENEKNSLRKA AELLETKLSR ADKLVSGLSS ERSRWQDSIA ELDGQLSFLV
GDCAVAAAFL SYAGAFVGHY RQELVKTCLQ AVRKLEVPAS PDFNFARFLA VPTDVRDWNI
QGLPTDEFST ENGLLVTRGN RWPLMVDPQG QANKWAKAYH GRALRVIDTK APDTARVLEN
AVQFGTPVLL QDVGAEIDPS LDPILLKAII TENGRKYLKL GDKKLDYNDR FLFWMTTRLP
NPHYPPEVCA KCTVVNFAVK EKGLEDQLLG FLVRLEQPKL EEDKSALVIA VAANKRKLVD
LENLILSLLK TASGSLLDDE GLINTLQASK QTSEQVSEDL RVSQETEKQI DAARDAYRPS
AVRASLLFFV LNDLAGIDPM YQFSLDAYFD MFRMSIDKSR KPKGTLDVKE RNRALNLYHT
DAVYKNTCRG LFEKHKLLFS FQMCVKKMQS EGKVNADDYL FLLRGGIVVD RESAPPANPS
ADWISEAQWE QATLLGKVAG FKSLEGSLEQ NNRAWRAWAR SECPETATLP GEWQTRIDDL
QRMVLLRVFR PDRVVFAARR FVAKNLDPTF VEPPPMDLAQ VYADSTPYTP VIFVLSPGVD
PSAMLRDLAA SSGTTVEEIS LGQGQEAPAR RLLAQGLKTG FWVFFANCHL SISWMPELEA
LVDAYCNGEP AAPHAQFRLW LSSDPHPAFP IPILQRGLKI TTEPPKGLRA NLLRLYAGLK
PDRFASALRP LKYRKLVFSL CWFHAVLLER RKFGSLGWNI PYGFNDSDFA VCESILRLYL
DEYEETPWEA LKYLIAEANY GGRVTDDRDR RLLIVYVDQF FSEALLAKKA ARLSPLDTYY
IPDDNDTAAV VTYIKSLPST ADPPEAFGQH ANADISSQMA ETTTLLSTLL SLQPRTADAG
GLSREDTTLA LIDSLLEQVP APIGGDQSNA GDPNPLRIVL LQEVGRYNQL LGRVRSSLVN
LRRGIKGLVV ISPALEQVYD ALYGGQVPDM WKTAYPSLKA LGPWVRDLVL RIEQMAKWAA
DGPPKVFWLS GLTFPTGFLT ALLQSTARRN GVAIDDLSWE FTPVDLDEVA VTTMPKDGAY
IKGMFLEGAR WDMDKMTLAD AGPMELECRM PIVHFKPVDN KRGRQGKGLY ACPLYMYPVR
TGTRERPSFM INVDLKSGAK DPTYWTKRGT ALLLSLAT
//
