ID A0A0G4IS01_PLABS Unreviewed; 497 AA.
AC A0A0G4IS01;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PPM-type phosphatase domain-containing protein {ECO:0000259|PROSITE:PS51746};
GN ORFNames=PBRA_006063 {ECO:0000313|EMBL:CEO97949.1}, PLBR_LOCUS5378
GN {ECO:0000313|EMBL:SPQ98163.1};
OS Plasmodiophora brassicae (Clubroot disease agent).
OG Mitochondrion {ECO:0000313|EMBL:SPQ98163.1}.
OC Eukaryota; Sar; Rhizaria; Endomyxa; Phytomyxea; Plasmodiophorida;
OC Plasmodiophoridae; Plasmodiophora.
OX NCBI_TaxID=37360 {ECO:0000313|EMBL:CEO97949.1, ECO:0000313|Proteomes:UP000039324};
RN [1] {ECO:0000313|EMBL:CEO97949.1, ECO:0000313|Proteomes:UP000039324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3 {ECO:0000313|EMBL:CEO97949.1};
RA Chooi Y.-H.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SPQ98163.1, ECO:0000313|Proteomes:UP000290189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Fogelqvist J.;
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Enzyme with a broad specificity.
CC {ECO:0000256|ARBA:ARBA00003302}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the PP2C family.
CC {ECO:0000256|RuleBase:RU003465}.
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DR EMBL; CDSF01000081; CEO97949.1; -; Genomic_DNA.
DR EMBL; OVEO01000009; SPQ98163.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4IS01; -.
DR STRING; 37360.A0A0G4IS01; -.
DR EnsemblProtists; CEO97949; CEO97949; PBRA_006063.
DR OMA; WANALVN; -.
DR OrthoDB; 202023at2759; -.
DR Proteomes; UP000039324; Unassembled WGS sequence.
DR Proteomes; UP000290189; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Mitochondrion {ECO:0000313|EMBL:SPQ98163.1};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000039324}.
FT DOMAIN 189..486
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 53797 MW; 83BDC38D2FBF4204 CRC64;
MDASDHDVVA PPESAPDVPS PKSLSDDVFV GKESPVASSK DKCDEPVDEK KGAAIEIAAD
GAQALNEIET GAGDSDNQKE PSSNPDSLSP DRVSNQFVAR HDANIGEKVD ITPQRAALYK
DTGEEEIHEP PELVSDTVQR EPDIVRQTRQ ASVGQSSHDP RKSLSVVVVE LSATRAVQTP
LSMSKFSLQS GYYGMQGRRP TMEDFHAQIQ HPEFNNLVPA VDLDGRQRHF FAIYDGHGGP
WCAEYCSRTL HQNLIRNPLF KDDSKKALHD AVVETDDTFC ALIRDKGLSE SSGTTAIVAY
IVDDLLLVAN VGDSRAVMCR AGTAVSLSQD HKPNRKDERA RILEMGGFVG RTLSQARAEA
GPGGVIWSNM CNCACLQAAG PGIPPYRVYP GGLAISRSIG DLEMKATRLV VNTPEIAEVP
LTDADEFIIL ACDGVWDVLS NDEAVKHVRA FRKRMGEHPM EAAKHLATLA FSEGSTDNIS
VLVIFLGKHD APMNPTP
//
