ID A0A0G4J189_PLABS Unreviewed; 1431 AA.
AC A0A0G4J189;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
DE Flags: Fragment;
GN ORFNames=PBRA_008393 {ECO:0000313|EMBL:CEP01081.1};
OS Plasmodiophora brassicae (Clubroot disease agent).
OC Eukaryota; Sar; Rhizaria; Endomyxa; Phytomyxea; Plasmodiophorida;
OC Plasmodiophoridae; Plasmodiophora.
OX NCBI_TaxID=37360 {ECO:0000313|EMBL:CEP01081.1, ECO:0000313|Proteomes:UP000039324};
RN [1] {ECO:0000313|EMBL:CEP01081.1, ECO:0000313|Proteomes:UP000039324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3 {ECO:0000313|EMBL:CEP01081.1};
RA Chooi Y.-H.;
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CDSF01000108; CEP01081.1; -; Genomic_DNA.
DR STRING; 37360.A0A0G4J189; -.
DR EnsemblProtists; CEP01081; CEP01081; PBRA_008393.
DR OMA; VSLHCQN; -.
DR OrthoDB; 2786103at2759; -.
DR Proteomes; UP000039324; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015918; P:sterol transport; IEA:UniProt.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR032190; NPC1_N.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45727; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR PANTHER; PTHR45727:SF2; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR Pfam; PF16414; NPC1_N; 1.
DR Pfam; PF02460; Patched; 1.
DR Pfam; PF12349; Sterol-sensing; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000039324};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 328..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 683..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..738
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 750..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 786..811
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1107..1125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1131..1154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1161..1181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1187..1212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1233..1252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1264..1288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 648..811
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1295..1362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1297..1321
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1322..1340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1342..1362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1431
FT /evidence="ECO:0000313|EMBL:CEP01081.1"
SQ SEQUENCE 1431 AA; 153683 MW; 473B17D6567304D2 CRC64;
MTMNRGVRTG KYEHAPGVRS KCAADIAPPA RPRGVAVTVA HAASAAAMAP SSAAGHPRRV
VVGALLGVVV VAATACADVI RQPGWCVAYG FSGASDDERF VNVVANVRAQ PVTAGFYDGD
ADLRTVCPSL ANETNLCCDV RQFGQLASQV QQALVILARC NACYRNFREF FCQYTCSPNQ
SLFKEITATT TSALNATVVR STNYYIGDGY GQAFFDSCKD VEFGATGRKI FDMFFDGAKT
PREWFDFLGR DEEHGDGRSP EWIRFPAADE DARAKGIAPL DAVPDLITRC NTTEPSLACA
CSDCNDACPP MSTLDVAAAD LPSPGHDAFF YGLAVPVIVF LAFVWVAVIR SVSRSSRVLM
RFPEDESDAG ARADVAASSS RIGNAFGSLG RRIGRHPIAW MGTSVAVVAV VAIVGVPRVV
LLEDPVRLWT NARSEAYREK VAHDAAFGPL FRVEQLIVKS ADGRPLFRDG VALPLLVNLQ
GLLQQLKQMT VASDATPGRN VSLDSVCYRQ GPGQPCLVQS VLGYWADPLT ARSDEGRLLQ
HLEDCTTNNF ADDCMGRSGL PTMSNVALGG YDLAARDYMN ATATIVTILL NGSASDAGGL
ADAQQWERAY IAFIQDALRD GVLGPGLSAT YSSEQSLQTE LNAQVSASAS TVLVSYLCMF
LYITFALGDC FPVRYLLRST RALLALVAIG VVILSIVSAV SICAIGGVEI TLIIGDVIPF
IVLAIGVDNV FLIFKAFSTQ PKRLAHEERL ANALSAVGPS ICLTSACEAL AFLLGMFTSM
PAVRAFAVYA AVAVICNLVL QVACFSAAIV LDARRRDRNQ TGRGAPLTEA EAAEQYDPIE
LFMRNVLSPC LEQTIVKLAV VAAFTALAGY SLHLFRTNLA LGLEPAVALP SDSYLQAYLR
DVATELRVGP PMFLVVPGGG DMALVETQNR LCSIRQCNHD SLGALAALAA SLPHATYVDT
GVSNWVDDYL QWTNAPFVRV GPSACCRIHL RTGAYCDPDD DDDDDQCREC VDGDGRDVHN
QVVVDPATGR LTPEAFQRFL PGFLQSTCSQ ACAHCGVPHL RNLQRRALGQ GNVSLGAVQF
QAYHTVLKTQ PDFIAALKSS RSLVHQMSSL TGLPVFAYSV FYVYFEQYLT IEAVASLSLT
LGLCAVIVLC VVLLGDLDVG LVVGGVITMI VADVIGLMTL ASCMLNAVSV VNLVTGLGLA
VEFCVPVVHR FVGIGGGSRD QRVRQALSDT GSSVVRGIVL TKVTGLAVLF LSRTPLIQVY
YARMYMLICA VGALHGLVFL PVLLSLLAPD VADTSSGQGD DDARHPLLQH DRDRHTSTNR
ETLYSTRDVG RSTMASAGSQ RLSRDEYKKQ RELDELRKSG AVPAAVDEDG RMINPHIPKY
ISEAPWYLNA SQHPSLKHQR ADAPAPPSDI HRYRRRGLLA SATATTTATR F
//
