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Database: UniProt
Entry: A0A0G4JUQ5_9GAMM
LinkDB: A0A0G4JUQ5_9GAMM
Original site: A0A0G4JUQ5_9GAMM 
ID   A0A0G4JUQ5_9GAMM        Unreviewed;       602 AA.
AC   A0A0G4JUQ5;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   18-SEP-2019, entry version 26.
DE   RecName: Full=Glutathione-regulated potassium-efflux system protein KefB {ECO:0000256|HAMAP-Rule:MF_01412};
DE   AltName: Full=K(+)/H(+) antiporter {ECO:0000256|HAMAP-Rule:MF_01412};
GN   Name=kefB {ECO:0000256|HAMAP-Rule:MF_01412};
GN   ORFNames=BN1221_02074 {ECO:0000313|EMBL:CPR16438.1};
OS   Brenneria goodwinii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Brenneria.
OX   NCBI_TaxID=1109412 {ECO:0000313|EMBL:CPR16438.1, ECO:0000313|Proteomes:UP000044377};
RN   [1] {ECO:0000313|Proteomes:UP000044377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OBR1 {ECO:0000313|Proteomes:UP000044377};
RA   Paterson Steve;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Pore-forming subunit of a potassium efflux system that
CC       confers protection against electrophiles. Catalyzes K(+)/H(+)
CC       antiport. {ECO:0000256|HAMAP-Rule:MF_01412,
CC       ECO:0000256|SAAS:SAAS01082428}.
CC   -!- SUBUNIT: Interacts with the regulatory subunit KefG.
CC       {ECO:0000256|HAMAP-Rule:MF_01412, ECO:0000256|SAAS:SAAS01076620}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01412, ECO:0000256|SAAS:SAAS01082436}; Multi-pass membrane
CC       protein {ECO:0000256|HAMAP-Rule:MF_01412,
CC       ECO:0000256|SAAS:SAAS01082436}.
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2
CC       (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01412, ECO:0000256|SAAS:SAAS01076602}.
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DR   EMBL; CGIG01000001; CPR16438.1; -; Genomic_DNA.
DR   RefSeq; WP_048637232.1; NZ_MJLY01000011.1.
DR   EnsemblBacteria; CPR16438; CPR16438; BN1221_02074.
DR   OrthoDB; 941006at2; -.
DR   Proteomes; UP000044377; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015503; F:glutathione-regulated potassium exporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   HAMAP; MF_01412; K_H_efflux_KefB; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR004771; K/H_exchanger.
DR   InterPro; IPR020884; K_H_efflux_KefB.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003148; RCK_N.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR00932; 2a37; 1.
DR   PROSITE; PS51201; RCK_N; 1.
PE   3: Inferred from homology;
KW   Antiport {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS00460756};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01082435};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01082425}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000044377};
KW   Ion transport {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01092081};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS00460792};
KW   Potassium {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01082424};
KW   Potassium transport {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01082430};
KW   Reference proteome {ECO:0000313|Proteomes:UP000044377};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS00460753};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS00460739};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01412,
KW   ECO:0000256|SAAS:SAAS01092095}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM     32     50       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM     56     75       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM     87    109       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    115    135       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    147    171       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    183    201       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    213    231       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    237    256       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    268    288       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    294    312       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    324    343       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   TRANSMEM    355    376       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01412}.
FT   DOMAIN      402    524       RCK N-terminal. {ECO:0000259|PROSITE:
FT                                PS51201}.
FT   COILED      573    593       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   602 AA;  66551 MW;  5C7802F2F641A6CD CRC64;
     MESSTLLTAG VLFLFVAVVA VPIAARLGIG AVLGYLIAGI AIGPWGLGFI RDVDAILHFS
     ELGVVFLMFI IGLELNPKKL WTLRRSIFGV GAAQVGVSTL VLGGVLYLTD FSWQSALIGG
     LGLAMSSTAM ALQLMREKGM NRNESGQLGF SVLLFQDLAV IPALALIPIL AGVQGEIDDW
     NQVALKVAAF AGMLIGGRYL VRPLFRFIAA SGVREVFTAA ALLLVLGSAL FMEALGFSMA
     LGTFIAGVLL AESEYRHELE IAIEPFKGLL LGLFFISVGM ALNLGILYVH IVKVLIAVLI
     LVAVKGTVLY VLARINRMRR SERLQFAGVL SQGGEFAFVL FSAASTYNVL QGDQLPLLLV
     TVTLSMMTTP LLMQLIDRIL TRRYNTVDVP DEKPFVADDE PQVIVVGFGR FGQVIGRLLM
     ANEMRITVLE RDISVVSLMR SYGYKVYYGD ATELELLRSA GAEKAQSIVI TCNTPEDTMA
     IVHLCQQHFP HLELLARARG RVEAHELLQA GVKHFSRETF SSSLELGRKA LMSLGMHPHQ
     AYRAQQHFRR LDMRMLRELM PQLQNDVAQI SRVKEARREL EDIFQQEMQH ERRRLDDWEE
     FE
//
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