ID   A0A0G4KHX0_9PEZI        Unreviewed;       576 AA.
AC   A0A0G4KHX0;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN   ORFNames=BN1708_009433 {ECO:0000313|EMBL:CRJ96986.1};
OS   Verticillium longisporum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=100787 {ECO:0000313|EMBL:CRJ96986.1, ECO:0000313|Proteomes:UP000044602};
RN   [1] {ECO:0000313|EMBL:CRJ96986.1, ECO:0000313|Proteomes:UP000044602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VL1 {ECO:0000313|EMBL:CRJ96986.1};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CVQH01001114; CRJ96986.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G4KHX0; -.
DR   STRING; 100787.A0A0G4KHX0; -.
DR   OrthoDB; 1820836at2759; -.
DR   Proteomes; UP000044602; Unassembled WGS sequence.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR   Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR   Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR   InterPro; IPR044611; E3A/B/C-like.
DR   InterPro; IPR000569; HECT_dom.
DR   InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR   PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR   Pfam; PF00632; HECT; 1.
DR   SMART; SM00119; HECTc; 1.
DR   SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR   PROSITE; PS50237; HECT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW   ECO:0000256|PROSITE-ProRule:PRU00104}.
FT   DOMAIN          222..576
FT                   /note="HECT"
FT                   /evidence="ECO:0000259|PROSITE:PS50237"
FT   ACT_SITE        544
FT                   /note="Glycyl thioester intermediate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ   SEQUENCE   576 AA;  65003 MW;  76779C396208B6B6 CRC64;
     MTGNKEGLAS SPTAQSALQP LLAQLDLLSI NTTPRLEFTA AERAVHEARA STLLLDWAKT
     VMLREWNGRP EVSCNSSFGG AVALIAAMYE KRHSLLLGDA QFRVDYFADR LDSINMPVEW
     LSHKTTQHKK HMLDFPFIFN PSTLVSYFRS INFLRMSRSY EESSSLQTRM KAIVAPGGLI
     TDPHHRVVLQ DLLQTASGKF LVLDISRDGV VRDAFDQLWR REARELLRPL KVHLGEEGGE
     EGFDSGGVQQ EFFRLAIAEC LDPDFGAFTV DERTRMAWFV PGSIVPVWKF ELLGILVSLA
     VYNGLTLPIT FPKAMYRKLL GEPVDELHHI ADGWPDLASG LTTLLEWDEK DGAVEDVFAR
     TYEFSVSMFD QPISREMNSE NPNWPQLKAE SESLAAQNPA DAPLVTDENR NAYVSDYIRY
     LTDVSVRPQF EAFLRGFRAC LHPKSLGLLT PPLLQSVVEG VQDIDIAELR RYTRYVGWDA
     SHRAVHDFWS IVKRYDDTMK RRLLEFVTAS DRVPVGGMRN LQFVVQKNGE EEGEGGHLPT
     AYTCYGTLLL PEYESKDVLR QRLAMALENS KGFGFA
//