ID A0A0G4KV59_9PEZI Unreviewed; 461 AA.
AC A0A0G4KV59;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=ferric-chelate reductase (NADPH) {ECO:0000256|ARBA:ARBA00012668};
DE EC=1.16.1.9 {ECO:0000256|ARBA:ARBA00012668};
GN ORFNames=BN1708_010869 {ECO:0000313|EMBL:CRK13576.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK13576.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK13576.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK13576.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 a Fe(II)-siderophore + H(+) + NADP(+) = 2 a Fe(III)-
CC siderophore + NADPH; Xref=Rhea:RHEA:28795, Rhea:RHEA-COMP:11342,
CC Rhea:RHEA-COMP:11344, ChEBI:CHEBI:15378, ChEBI:CHEBI:29033,
CC ChEBI:CHEBI:29034, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349; EC=1.16.1.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000496};
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DR EMBL; CVQH01004780; CRK13576.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4KV59; -.
DR STRING; 100787.A0A0G4KV59; -.
DR OrthoDB; 2787294at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0006826; P:iron ion transport; IEA:UniProt.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR InterPro; IPR034751; Yippee.
DR InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR PANTHER; PTHR32361; FERRIC/CUPRIC REDUCTASE TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR32361:SF24; REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10820)-RELATED; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR Pfam; PF03226; Yippee-Mis18; 1.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
DR PROSITE; PS51792; YIPPEE; 1.
PE 4: Predicted;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022982}.
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..110
FT /note="Yippee"
FT /evidence="ECO:0000259|PROSITE:PS51792"
FT DOMAIN 170..308
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 461 AA; 52394 MW; 68AA96AE8D80AF6E CRC64;
MGLAYNTYLN SSKIYGCKTC KAHLANHEDI ISRNFRGQHG KAYLFNNVVN IDMGEPSERN
MTTGRHIVRD ITCRQCKETV GWKYDKAYET TEKYKEGKFI LEAELLCNGT CGFAAIFIQA
WSPIRHAFYE IFKLLHIALA ILAVMGTWYH LHLKDLPQLR YLIAAIVIWA VDRLWRVFRV
IYGNFGRGGS RALVEALPGN AVRVTVNMAR PWTFRPGQHA YMYMPSLSYL QSHPFSVAWS
EDAEDPSSEK LTMNRQDILE MRKTTMSFVI RGRTGFTNTL FQKASACPRG QMHTTCMIEG
PYGELHSMKS YGTVMLFAGG VGITQAVPHV RDLVIGYANG TVATRRITLV WVIQSPEHLE
WIRPWMTQIL AMDKRRDVLR IMLFVSRPRS SKEIHSPSAT VQMFPGRPNI DTLLAAEMEQ
QVGAMGVTVC GPGVLSDDVR RAVRARQYDG EIDFVEEAFS W
//
