ID A0A0G4MDQ9_9PEZI Unreviewed; 586 AA.
AC A0A0G4MDQ9;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
DE Flags: Fragment;
GN ORFNames=BN1708_016077 {ECO:0000313|EMBL:CRK32115.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK32115.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK32115.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK32115.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CVQH01022017; CRK32115.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4MDQ9; -.
DR STRING; 100787.A0A0G4MDQ9; -.
DR ESTHER; vera1-c9ser5; Fungal_carboxylesterase_lipase.
DR OrthoDB; 662485at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02124; PA_PoS1_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 21..586
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005118081"
FT DOMAIN 108..290
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 329..401
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 433..566
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 66..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 586
FT /evidence="ECO:0000313|EMBL:CRK32115.1"
SQ SEQUENCE 586 AA; 62555 MW; BA843E1DC7552E43 CRC64;
MVRSNIFLSL LAAASTVVSA APQPQTIPDL DTAEEKATEL GKMAGVRSIR TLKEYHRPDD
KVIWTGNSGR EYHKSRKRDK QDGGRDHDAF TPHLMTQVDM LRDAGYTGKV FKIAVIDTGI
DFKHPALGGC FGKGCLVSYG HDYVEGDNVE EPTMDCDGHG THVAGTIAAQ SNPLGFTGVA
PDVTLGSYKV FGCNGTAPSD AIAAAFAQAF EDGSDIISAS LGGDQGWSQE EGSVIVQRIV
EQGVPCVIAA GNSGASGLFF ASGPADGIGS TAVASFDNLV IPQLLTESTY SIDDDGEVDF
GWHEGAPAAW ADVELPLYAT SLDTEVFDDA CDPLPSDTPD LNNHIVLIRR GTCTYDEKAA
NAADKGAKYI MFYNNVPGIE DVSSAHARIL AVAMTTAEEG EYWVQALAAG SKVTLHMTDP
IESDAVLEHG RQLRHPLPVL VWIFGGGLYT GSIADPQYNL SGIVKVSQDM GQPVIAVAMN
YRLNMYGFLQ TPQLLAEGSS NAGLLDQRLA LRWIQENMAA FGGDPDRVVI WGESAGAQSI
AYHLFSYEGR DDGLYRGAIM ESGGPTGAQV QNLPYYTVPV ENLTRS
//
