ID A0A0G4MFE6_9PEZI Unreviewed; 796 AA.
AC A0A0G4MFE6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN1708_005960 {ECO:0000313|EMBL:CRK33008.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK33008.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK33008.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK33008.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CVQH01022416; CRK33008.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4MFE6; -.
DR STRING; 100787.A0A0G4MFE6; -.
DR OrthoDB; 1330350at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 2.
DR CDD; cd09917; F-box_SF; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 2.
DR Pfam; PF16643; cNMPbd_u2; 1.
DR Pfam; PF00646; F-box; 1.
DR SMART; SM00100; cNMP; 2.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 75..192
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 277..407
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 543..583
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 796 AA; 88311 MW; BCB9F5F89995FC65 CRC64;
MRRHRSGSSP SPYRALANQN GGGHGAGGIP DSMSLIRSFN VEATPTRPVR PSPLTASTIR
DMPLDLVDRI RSFPLFQSAS EDFLAAIGNH LRPQVHAAQD TILHEGEDAR AMYWIVRGVV
AVTSRDGEAV FAELKAGSFF GEIGVLMDVP RTASIVARTK CLLVVLKKEN LQTELPRFPE
MEQAIRQEAQ ERLNILKKKR KESSHSDKSP PIGTSISREP APGEVSTGEV GMIKEGSVHN
SKKRKSPSPG AIEDPAAGSA LGSGFVNVRK TLKEFPLFST LPSDILHFLG LSAQPKTYSP
FTDIVRQGAP GNDIFFIVRG EAEVVREPAK SEDPFRKMRR GSYITPRLKA GQYFGEVASL
GLSEGRTASV RSITTVECLM IDGDALEELW KMCPPDIKLQ VEETARKRYR KTDEDVDMHD
VNTEQQRSKS DPPTPTTPKV LPHVTFTTPS KPTSPTREDA GEAMEPKDPD PYLSVNMENL
RNRRRNSLAP PTPQPDAPSP SVLNGRYQPL DTTPIRFGVP QWPSDSEEVP PKRARILPHR
PLSMQTPSLP DKVLVSALQL MSVGELVRLR LVSTHWRKVI EKDPGVCIHA DLSPYNRRVT
DHTIRTVIGP FLGNRPEMID ISNCFHLTDE GFKSLWEQCG RNVKRWRMRS VWDVSANQIL
EMAENAKDLE EVDWSNCRKG ISVRGCVRVT GNGVENMLDG CGRLTWVDVS QCRNLEGWIR
TGGVARWGFD ERGGNGLPSP SSSDDGDRPK LMARAMSMSK NSMGHNVGVP GRTMSFRRRT
RKPVRFIVEK GTGVLR
//
