ID A0A0G4MVN6_9PEZI Unreviewed; 3233 AA.
AC A0A0G4MVN6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Vacuolar protein sorting-associated protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN1708_007694 {ECO:0000313|EMBL:CRK38229.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK38229.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK38229.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK38229.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
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DR EMBL; CVQH01025305; CRK38229.1; -; Genomic_DNA.
DR STRING; 100787.A0A0G4MVN6; -.
DR OrthoDB; 199953at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR015412; Atg2/VPS13_C.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR017148; VPS13_fungi.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF09333; ATG2-VPS13_C; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
DR PIRSF; PIRSF037235; VPS13_fungi; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 139..380
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 594..830
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 2005..2580
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2829..3005
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 3011..3091
FT /note="Atg2/VPS13 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09333"
FT DOMAIN 3102..3207
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 834..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 890..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1398..1429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1755..1835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 836..850
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..908
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1407..1429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1781..1800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3233 AA; 362412 MW; C721CB39558E88E9 CRC64;
MLEGLVAGLL NRFLGMYVNN FDPKQLKVGI WSGDVKLRNL QLRKEALDQL KLPINVFEGH
LGELTLIIPW SNLSGAPVKV FIEDVFLLAS PKEDAAYDED EEERRKQRIK MEKLDSAELL
KERSQEGLSS EEQKKNQSFT QSLVTKIVDN LQVTIKNIHV RYEDSISTPG HPFALGVTLQ
EFSAVSTNGE WTPTFIQDST KSTHKLAKLG ALAVYWNTDT ELYGPGREID QEDRPTLTHE
EMVAKFKGMI AKPDETKPDY QFVLRPVSGQ AKIVLDKTGD IHIPKTKASL LFEEIGLVLD
DDQYRDGLMM VDLFHYFIRH QEYKKLQPKG VTPKEDPRAW FKFAGDAILS KIHERNRRWS
WEYFRERRDD RKRYIELFKK RKQQQQFSAE DSADIEALER RLDYEDLRFW RSLGRNQLKK
ENAAALKSKP AQPQQQGWLA WAWGSKPAEE QHSDMEENTQ ITEEQKRELY DAIDWDEKTA
LAESVDVPRD SVKIQVEASL STGSFTLKKN HNGKLKDLIS LHFDVFKAKA LQRPDSFLAA
LSLGGLRVND GTTPNSLFPE IVRVKDAPET QERKALTIEE LESCDDEPFF NIEVEQNPID
REGDIAVVGS LKPLEIVWNP NSVVGVADFF RPPERHMESI SALMESAGAT VEGFREQTRA
GLEFALEEHK TINAQLDLQA PLIIVPVSIA TKESTCLILD AGHISVNSKL VDQDTMKQIQ
SKQRQQYSNE DFERLESVMY DKFLVKLTST QLLIGPSIKA TKKQLIDRDA SQPLHIVDQI
NIDFVVETSI LPKAPNLTKL KVSGHLPVLQ ATMSDAKYKN LMRVIDVAIP KFGDDKTAQN
KSKEQTRPTS RSSKASRPRL ASSASNRSRK DARRKSSQFP FLQQQTAIVI DDDDLDEDDN
DNYEDASDGV DNEQITMQQR SFELKFKVDT LKGSLYRSDP DRKKPDELLV ELVANDFDLE
FFLRPYDMSA EVSLGSVTMD DFVDDPPAEF KSIISSGDVE DREQKRSLVK VKFTKVNSQS
PEFMPVYEGV ETNVTAAIST INLIVTRKTL LTLLDFILAT FTGDNNEAVS KREQKAIEAA
ESDDNEVEVA VDTPTEDAQA NTASIRVKAD LKSIRLILNN DGIRLATLSF NHADVGVFLR
GKTMRVSAKL GDLNLVDDVN QGVPDDSPLR RLIAIEGDDL ADFRYETFDA ENPKTYPGYD
SSIFLRAGSL KLNFLEEPFR KIIDFVVKFG KMQAIFNAAR QAAANQANQI QQSTSRFKYD
VVVKTPIVVF PRVVQLGQPK RDLLTAYLGE IYAQNKFAPL DDSEDAQIAT KISAGIRNIR
LTSDFNYEDD KSEELELIDH VDLGFNVTYA EHQHGKKRPE LEIQGTMSDF NLKLTQYQLR
FLMEISKSVP AAFASDSDAQ VESAEQDVDE DTLKRARSMP VEKASGDDDQ LVDLSPELRS
RDKTWTTLDL VFQVQTIGME LIMAPEGKPV GNIETASLSR FSLDDTRVKT RMLNDGSLEG
EFLISSFTIH DSRSRDANKY RRIMTSLNKD VQQLMASVTM TGGKDKSLIA MVTVDSPRII
FALDYLFAIQ NFVTVGLTAE DPLAIDDESL LDVQSTEESD ADLDAASSRA VLTKHITASQ
QVDTTEATAG YGEKDKTPSA MNVAFRVNVV DAQVILIANP LSSSSEAIVL GTKQVLLSQQ
HALTFQISEI GMFMCRMDKF EDSRLRILDD FSIQMSMDSS KPGLTSIHVD VEPLILRLSL
RDILLALQIA SKATELSSSQ PQNDSKPSAV DEKARQLRQA GLKQRTASGK GPSTLAARTR
VTKSAGPGAK IAAAQGSQAN EFESDGALQK PPRQREELTA TIDGIRIVLI GDTHELPIFD
LGIKCLTVTA EDWSSNLKAG TAVDIYMNVY NFSKSSWEPL LEPWQMGVGI AKEQDTGLLS
IDVTSKKVFD VTLTTATIAL ASKSFAFLSQ DEDVLGKPRG VDAPYRIRNY TGFEAVVQSK
STVTDEVTTT RLEDGQQVPW SFEPWEKMRE NLLAESSSND VTIQLEGSGF DPVKSVRLNR
EGEFIYCLRP KTDTVLHRLL VEVSLGQDNV KYVTLRSPLV VENDTQIPVE LGVYDAEEGH
LLKIEKISPG ESRPAPVGAV FLKSLLIRPD SGFGYAWSSE TLWWRDLLKR PTRTMVCKGE
NGDPFYFQVN ATFDKANPLT RNYPYMRLKI SPPIVLENLL PHDFKYRIYD KDTKKDWTNF
LRKGGLSPVH VVELSHLLLL SIDMQDTVFK PSDFAVVNPG HSDEFKKEKK LICKDQDGLQ
LTLQLHYFKI PDSGGAFRVT VYSPYVILNK TGLDLSIRAK SFMQSAKAAA GQSLLTQGLE
AGQERPKATP FMFSYGNDDN RNRTLLKIAD SDWSKPQSFD AIGSTNEVVL PSTKKNSEIH
VGITIESGEG KYKMTKVVTL APRFVLANKL DEEINVRESS ASGFMTLKPG ALQPIHFMQK
TAVKQLSLCH AGMNNDWTSP FNISDIGTTH IKIAKHGQRQ RLIRAEILME AATVFVHLSM
ETKNWPFSMR NESDTEFTFY QANPNVDEDG VEDRSGWKPI RYRLPPRSIM PYAWDYPAGK
FREIVLNTQG KERHVKLAEI GNQIPMKAVT ASGQQKIIDI NVAADGPTQT LILSNYRPSK
SLYRQKSRSG SRTNNAEGFE VKSQETGATF RAQLKLSGIG ISLINSQLRE LAYITFRDVQ
LRYQESQLYQ TVSLAVKWIQ IDNQLYGGLF PMILYPSVVP KKAQEVDAHP SLHAMVTRVK
DDSYGVLYIK YATLLLQQMT IELDEDFVYA VLDFSNIPGA AWSNSPDRGK LCDEELDIPE
PKQQQSGQDI YFELLNIQPM QLDLSFMRTE RVNAEDKTSS RNPLMFFLNV MTMAIGNVND
APIRLNALML DNVRVSVPAL TQNISNHYSQ EVLYQVHKIL GSADFLGNPV GLFNNISSGL
TDVFYEPYQG LILSDKPEDF ALGVGKGAAS FVKKSVYGFT DSFSKFTGSL SKGLAAATLD
KQFQDRRRIT RARNRPKHAL YGVTAGANSF FTSAASGVGG LVRKPLEGAE QEGAMGFFKG
IGKGVVGFAT KPAIGVLDMA SNVSEGIRNT TTVFDGSELE RVRYARFISA DGIVRPYNGR
ESMGQNWLKQ VDNGKYFNEQ YIAHLELPRE DMVVMVTYSR ILLIRSRRLT SEWDVPLKDV
QTIAKERTGL SLTLRGGTNG PFLPVGDESG RAFLYKMVAV AVEEFNRRFR GLE
//
