ID A0A0G9H4Y1_9GAMM Unreviewed; 811 AA.
AC A0A0G9H4Y1;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Mechanosensitive ion channel protein MscS {ECO:0000313|EMBL:KLD64556.1};
GN ORFNames=Y882_06725 {ECO:0000313|EMBL:KLD64556.1};
OS Dyella japonica DSM 16301.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Rhodanobacteraceae; Dyella.
OX NCBI_TaxID=1440762 {ECO:0000313|EMBL:KLD64556.1, ECO:0000313|Proteomes:UP000035481};
RN [1] {ECO:0000313|EMBL:KLD64556.1, ECO:0000313|Proteomes:UP000035481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16301 {ECO:0000313|EMBL:KLD64556.1,
RC ECO:0000313|Proteomes:UP000035481};
RX PubMed=25481407; DOI=10.1007/s10482-014-0344-8;
RA Naushad S., Adeolu M., Wong S., Sohail M., Schellhorn H.E., Gupta R.S.;
RT "A phylogenomic and molecular marker based taxonomic framework for the
RT order Xanthomonadales: proposal to transfer the families Algiphilaceae and
RT Solimonadaceae to the order Nevskiales ord. nov. and to create a new family
RT within the order Xanthomonadales, the family Rhodanobacteraceae fam. nov.,
RT containing the genus Rhodanobacter and its closest relatives.";
RL Antonie Van Leeuwenhoek 107:467-485(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLD64556.1}.
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DR EMBL; JPLA01000015; KLD64556.1; -; Genomic_DNA.
DR RefSeq; WP_046971110.1; NZ_JPLA01000015.1.
DR AlphaFoldDB; A0A0G9H4Y1; -.
DR STRING; 1440762.Y882_06725; -.
DR PATRIC; fig|1440762.4.peg.707; -.
DR OrthoDB; 9799209at2; -.
DR Proteomes; UP000035481; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR022249; DUF3772.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF12607; DUF3772; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..811
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002577090"
FT TRANSMEM 251..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..625
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..192
FT /note="DUF3772"
FT /evidence="ECO:0000259|Pfam:PF12607"
FT DOMAIN 624..689
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 701..778
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 791..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..811
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 87734 MW; 7DC396F024A8F203 CRC64;
MPILSRLLLI LLFAVASASP VLAQDTQNNG QIQQTVLATP DQLSTQLDQV KKTLTDKSKL
TDDILTGARS KTQAIQQQAD QLTTSLAPQA DALKAKLDVL GPAPAKGAPA ETPEVAAQRK
QLTKDQTDLT GQLTQSKLLS RESQQLLTEI AALRRNLFQA QISQRSASPL SMAFWSRFAQ
NLPDDSGNFR QLSQSVQGAL AQAWQPANRL PFILCLSAAV LLLAGGRRVF EYKMLDIAAR
YLPSGHLRRS AMAAVVTVGT TLIYGIAAWL IYLAVNWNGV FDEDLDELVR PLVRLMFYVA
TMAGLGRALL MVKHPSWRLP PISDNLATRL WPFPSLMAYS ALLLGVIERV TNDISASLST
AMAANALAAT VIGGLVAYAL VIMSRARRAL LSSGATPASR PLWVGVLVLC AFLGMLITLI
SVLTGYIALA FYVARQMLRA GFLIAALYVV MHLINDLCES VLSPDSRTGI RLQENFGFAP
ARLEQTATVL SGVGRAFLLM FAIPLILAPY GAGANELMDR GTRIFNGLSL GTLTINPTSI
FNAMVVLVVG YVIVRLLKRW LSKQLLPKTS LDVGMQMSIV TLLGYVGGIL VFVLVLGALK
VDVQSIAWVA SALSVGIGFG LQAIVQNFIS GLILLAERPV KVGDWVSISG VEGDIKRINV
RATEIQQGDR STVIVPNSQL ITQNVRNVTL ANAQGRVQIR LPMPLGTDPN KVRQIIFDIL
RNHSVTLNSP APTVQLDSID SGSMMFVCTA YVNNPRDSGT VKSDLLFEII DRLRKANLPL
TTPQDMVVRT MQHDPATPPS PPTTVFPGKP T
//
