ID A0A0H0YQ65_LACCA Unreviewed; 645 AA.
AC A0A0H0YQ65;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=AAW28_03070 {ECO:0000313|EMBL:KLI76694.1};
OS Lacticaseibacillus casei (Lactobacillus casei).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1582 {ECO:0000313|EMBL:KLI76694.1, ECO:0000313|Proteomes:UP000035289};
RN [1] {ECO:0000313|EMBL:KLI76694.1, ECO:0000313|Proteomes:UP000035289}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N87 {ECO:0000313|EMBL:KLI76694.1,
RC ECO:0000313|Proteomes:UP000035289};
RA Zotta T., Bassi D., Parente E., Ricciardi A., Ianniello R.G., Reale A.;
RT "Genetic and physiological basis of aerobic metabolism in Lactobacillus
RT rhamnosus and Lactobacillus paracasei: basic and applied aspects.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLI76694.1}.
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DR EMBL; LCUN01000009; KLI76694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H0YQ65; -.
DR PATRIC; fig|1582.46.peg.2362; -.
DR Proteomes; UP000035289; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.20.1270.70; Designed single chain three-helix bundle; 2.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF07554; FIVAR; 2.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 619..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..342
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
SQ SEQUENCE 645 AA; 68881 MW; 207488599DF072D0 CRC64;
MSDAELNQYI SKMSLDEKIG QMFVSRTPQD TAQARADVAK YHLGGLIVYG ADFTSVEGST
PEAAQAAFKN KLQSFQDSAK LPLLIGVDQE GGSVSRLSQN PLIANGRAFP SPQALFAEGG
MAKVTQEAQQ VGTILKNLGI NWNYAPVADS TADTDSFIYP RTIGQDYTAT ADYISQVVPA
WQNTGIAATV KHFPGYGSAV DTHTDFAVVT KSEEAFEKED LLPFKAGIDA GVDSIMIAHI
VMQSVDPVYP ASLSKRVVTD LLRNELGYKG LIITDALGMG AITKFAASHN NVPVDVLAVA
AGNDCIMNDD YATAIPQIHQ AVTNGQLSEQ AIDQHVFRIL SLKRKLGLLT TAQLETKQVR
VDNVAYDQAK KTATVSGTVV DSNWQTGEPL TVKDDQGLVV ATADVGAGGK FNFTIPLTAK
AQQLTLTTGL PGIEDAQVTI EPLQVAKVDK TALQTLVNQG AAYVANDYTS GSWGKYQVAL
AAANQVLADQ EATQDAVDQA VQTLQTAIAG LVKTNVKTNK DALQQLIEQV LAYDAKRYTN
STWEKLETAL AEAKQVLADK NATQPVIDHA VQVLKAAAIG LETQNSGAGQ QKKVAFTGKK
SPNKVDGDNN VMPRAGEKVV NGLVMLGVVL ILTTAGMIWW RKARD
//
