ID A0A0H1B9A3_9EURO Unreviewed; 635 AA.
AC A0A0H1B9A3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=EMPG_10764 {ECO:0000313|EMBL:KLJ05791.1};
OS Blastomyces silverae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060906 {ECO:0000313|EMBL:KLJ05791.1, ECO:0000313|Proteomes:UP000053573};
RN [1] {ECO:0000313|Proteomes:UP000053573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 139 {ECO:0000313|Proteomes:UP000053573};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLJ05791.1}.
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DR EMBL; LDEV01003476; KLJ05791.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H1B9A3; -.
DR STRING; 2060906.A0A0H1B9A3; -.
DR OrthoDB; 2785946at2759; -.
DR Proteomes; UP000053573; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR Gene3D; 1.10.220.160; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 2.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR12197; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD; 1.
DR PANTHER; PTHR12197:SF273; MYND-TYPE ZINC FINGER PROTEIN SAMB; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000053573};
KW Sporulation {ECO:0000256|ARBA:ARBA00022969};
KW Transferase {ECO:0000256|ARBA:ARBA00022603};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 273..597
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 86..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..136
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 70617 MW; 214C38B42458D532 CRC64;
MQREDATALL YVDPHNPMRH LQRGIIHSKL GYPDLAAADA YRALTLFEAV IDPDSSEYRA
RKKVGLDAVE LAGSSGLVDG VAAISVRGGS DHDESENYDD DDADEDGHME EDEDGDEDED
EDGDEDEDEE EGFESISQDE YRENIRHIYI LLVKSLVQCG CMRDAYNFCI QAMDLPDSEL
QSSLSVFEEQ LSIIKRSFLD RQRSRQQKEG RGASADNQGQ GTDEGLLAKF QPANLDAQGH
ARRVLYPWNT HEPDRSAPET LQLLNERLKK IAPKCEVRAV ALPAMYHNTV DGNPSSKQEE
QEQEEASIQL GLVATEDIAP GETFLHESSL LTATNRLHDS LCDACNGPIP ELSATNSSVA
CGECEDTIFC SQECHDLAQE VYHAAECGQE GLESIGKDIQ DPKDKADYLY LLLLGRAIAM
AATQGIHPLD LPEVKYIWGD FHPLDDGMLP PTAVSSSSNN NNTANLQPPS ATLPFSFHLS
ILQPTRILEE MGLDPFATLP TYDTWVLNTL YAKFRGTASG RLSTWDGGPE VSAVHPLWCL
ANHSCDPNVR WEWGGEITFT VRREDERVKW DGRKSGDAGD EKWAGIKRGE EILNHYCDVG
LGVRERREWA MGALGGACRC ERCVWEEKQI DLDER
//
