ID A0A0H1BDT5_9EURO Unreviewed; 371 AA.
AC A0A0H1BDT5;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=DNA-repair protein complementing XP-A cells {ECO:0000313|EMBL:KLJ09212.1};
GN ORFNames=EMPG_15353 {ECO:0000313|EMBL:KLJ09212.1};
OS Blastomyces silverae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=2060906 {ECO:0000313|EMBL:KLJ09212.1, ECO:0000313|Proteomes:UP000053573};
RN [1] {ECO:0000313|Proteomes:UP000053573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 139 {ECO:0000313|Proteomes:UP000053573};
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLJ09212.1}.
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DR EMBL; LDEV01002396; KLJ09212.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H1BDT5; -.
DR STRING; 2060906.A0A0H1BDT5; -.
DR OrthoDB; 1344100at2759; -.
DR Proteomes; UP000053573; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd21077; DBD_Rad14; 1.
DR Gene3D; 3.90.530.10; XPA C-terminal domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000465; XPA.
DR InterPro; IPR022656; XPA_C.
DR InterPro; IPR022658; XPA_CS.
DR InterPro; IPR037129; XPA_sf.
DR NCBIfam; TIGR00598; rad14; 1.
DR PANTHER; PTHR10142; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR PANTHER; PTHR10142:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS; 1.
DR Pfam; PF05181; XPA_C; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00753; XPA_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053573};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 213..263
FT /note="XPA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05181"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 371 AA; 42610 MW; 0CECA63B9FD0BD04 CRC64;
MEAHQNKGTP PPRGNSIVSK TRTPLTPEQL HRIEIHRMKA KALREQHDAE ARSHSVPSGS
VTAGQKRPYS DISPSKPPMS SRDARSNKSY ERPLDEIRPA RNFSKYVEYD MSKMTDTKGG
FLTAEDDPHN KALNSGERDE KPAHMTLKEW ERHQLLQSLR RDKAGPFEPG LSILNTKEQR
SCRECGSIEI DWKWEETLKC AVCNSCKEKF PEKYSLLTKT EAKEDYLLTD PELKDEELLP
HLEKPNPHKA TWNNMMLYLR FQVEEYAFSP KKWGSPEALD AEFEKREATK KRQREAKFKS
KLHDLKKRTR VEAYRRNRQA ATGEGPGGHF GDDLGSGKHV HQWGRLVDNP DTGIGVKTCI
DCGMEIEELE F
//
