ID   A0A0H2LSU7_VARPD        Unreviewed;       252 AA.
AC   A0A0H2LSU7;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=DNA-binding transcriptional dual regulator Crp {ECO:0000313|EMBL:KLN53299.1};
GN   ORFNames=VPARA_56150 {ECO:0000313|EMBL:KLN53299.1};
OS   Variovorax paradoxus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=34073 {ECO:0000313|EMBL:KLN53299.1, ECO:0000313|Proteomes:UP000035170};
RN   [1] {ECO:0000313|EMBL:KLN53299.1, ECO:0000313|Proteomes:UP000035170}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TBEA6 {ECO:0000313|EMBL:KLN53299.1,
RC   ECO:0000313|Proteomes:UP000035170};
RA   Poehlein A., Schuldes J., Wuebbeler J.H., Hiessl S., Steinbuechel A.,
RA   Daniel R.;
RT   "Genome sequence of Variovorax paradoxus TBEA6.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KLN53299.1}.
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DR   EMBL; JZWI01000036; KLN53299.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H2LSU7; -.
DR   PATRIC; fig|34073.19.peg.5754; -.
DR   Proteomes; UP000035170; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SMART; SM00419; HTH_CRP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000313|EMBL:KLN53299.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000035170}.
FT   DOMAIN          6..104
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          139..206
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51063"
SQ   SEQUENCE   252 AA;  27722 MW;  7ABFAAA1C3B5F21C CRC64;
     MYLHPLIASV PPADRAALIR SSELRSYRRN ETVLLADTWT DRIFCVASGL LRAVDRDVTT
     DFIRRGDFFL GPSLSEDRYQ TTSTLVAALP SSVYLMPIAA IRRLCAVYPE VTIGLLEVAM
     KRITMIRGQL RRISSLSAEN LVGRVLHELT QLAPAGAGGY DKRITQAVIA SYSGLSREVV
     NKTMRDLESR GLVRRDEKGI HIPPNFASTD FGSLLPAAQD TPDVEAHEAH PMFDPELFAT
     PEGMGKTGPK AI
//