ID A0A0H2MG58_VARPD Unreviewed; 566 AA.
AC A0A0H2MG58;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Serine/threonine-protein kinase PknB {ECO:0000313|EMBL:KLN55825.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:KLN55825.1};
GN Name=pknB1 {ECO:0000313|EMBL:KLN55825.1};
GN ORFNames=VPARA_31920 {ECO:0000313|EMBL:KLN55825.1};
OS Variovorax paradoxus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=34073 {ECO:0000313|EMBL:KLN55825.1, ECO:0000313|Proteomes:UP000035170};
RN [1] {ECO:0000313|EMBL:KLN55825.1, ECO:0000313|Proteomes:UP000035170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBEA6 {ECO:0000313|EMBL:KLN55825.1,
RC ECO:0000313|Proteomes:UP000035170};
RA Poehlein A., Schuldes J., Wuebbeler J.H., Hiessl S., Steinbuechel A.,
RA Daniel R.;
RT "Genome sequence of Variovorax paradoxus TBEA6.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLN55825.1}.
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DR EMBL; JZWI01000015; KLN55825.1; -; Genomic_DNA.
DR RefSeq; WP_047785215.1; NZ_JZWI01000015.1.
DR AlphaFoldDB; A0A0H2MG58; -.
DR PATRIC; fig|34073.19.peg.3276; -.
DR Proteomes; UP000035170; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KLN55825.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035170};
KW Transferase {ECO:0000313|EMBL:KLN55825.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 541..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..232
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 265..535
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 61293 MW; 9935B3C78B3531D5 CRC64;
MSFEVDIGYS SQRGPRDVNE DFAGAVNAPP GDESRGLIAA IADGVSTGGR GLEAAQTTVM
GLLADYFATP DTWEPTAALD RLVAAQNAWL ADHNRRRQGS ATALTTLTAL VLHGQSYTLA
HVGDTRAWRV RADGEPATPL TQDHAFEHPD MRSRLTRAIG LDDQVRVDYA QGDVRVGDCF
VLTTDGVHGV LKPQRLAALA LQGGAEEASE ALVNAALDAG TRDNATALVI RVVGLDVRQL
DDELGDGRRL APPPLLKVGD ALDGYVVTGL VADTGVHLLY QARNAATREL VALKTLHPSR
ASDPQERAML AHEAWLGQRV GSGGFVRVHE RAENASALYI VFDWHGGRTL EQMRKSGARG
AVAEVVSAAI EVTKALGRLH RHGVVHRDIK PGNLHLGDDG RWRILDLGVA LSGREGPAQR
ELHAGTPSYI NPEQWEGAEA DTASDLFALG VTLYQWLGGH LPYGEIEPYQ VARYRRDPAA
LSRLRPDVPV WLDHLVRKAV ARDQRERFET AEEMLLALER GASRPVSAPA ATPLIRRDPA
ALYKIALAVS LLFNALLVVW LLFLPR
//
