ID A0A0H2RS17_9AGAM Unreviewed; 1589 AA.
AC A0A0H2RS17;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=RhoGAP-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SCHPADRAFT_875677 {ECO:0000313|EMBL:KLO12258.1};
OS Schizopora paradoxa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Hymenochaetales; Schizoporaceae; Schizopora.
OX NCBI_TaxID=27342 {ECO:0000313|EMBL:KLO12258.1, ECO:0000313|Proteomes:UP000053477};
RN [1] {ECO:0000313|EMBL:KLO12258.1, ECO:0000313|Proteomes:UP000053477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUC8140 {ECO:0000313|EMBL:KLO12258.1,
RC ECO:0000313|Proteomes:UP000053477};
RG DOE Joint Genome Institute;
RA Min B., Park H., Jang Y., Kim J.-J., Kim K.H., Pangilinan J., Lipzen A.,
RA Riley R., Grigoriev I.V., Spatafora J.W., Choi I.-G.;
RT "Complete genome sequence of Schizopora paradoxa KUC8140, a cosmopolitan
RT wood degrader in East Asia.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ085981; KLO12258.1; -; Genomic_DNA.
DR STRING; 27342.A0A0H2RS17; -.
DR InParanoid; A0A0H2RS17; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000053477; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09395; LIM2_Rga; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR23176:SF141; TRANSDUCER, PUTATIVE-RELATED; 1.
DR Pfam; PF00412; LIM; 2.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00132; LIM; 2.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Reference proteome {ECO:0000313|Proteomes:UP000053477};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 29..94
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 1320..1368
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 1391..1586
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 792..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1211..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1052..1124
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1158..1192
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..652
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..702
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 915..932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1219..1238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1589 AA; 172295 MW; 9EFAAF4894887934 CRC64;
MLAAVPSHLR ESTSFSAGPS TSASGEPDRF CAGCNRSVNS ETGGVVVAFG NSLWHVDCFK
CAKCGNLVNA DTNLLLLSDG SPVCANCYNC KICNLPILDE AVMTGDDSYH AACFTCRSCR
NRIDELVFAK TSQGFYCMKC HNERVARSRR HAAKQKQRER ERQGTKDQSS RPGAGVPAMP
SSTVDQNFLD ISQSSSTSES SGSWQHQHQH QHQPPQEQRS SPSRINGYPD VTSVDANVSA
ANASFMSTNS VVDAAVLRSD LDHRSASPAP PAVSITVESS ASPERHNGEE RTLPFRRRSH
SPDFVADVPT AATADGPPPP PYSITPPATQ VSFDADSARS SASYGHSHPG SGPVSPPISR
PTSYEQSRPG SSDRFAVNSP PDRSSSSSLG HVEVSVRSIN DQGFLPDRRD SGSGKKYDDG
TRPLSFLHPS TPASDRTVML SPGQSKRSKR GSMNPGLQLE ASRLQLDAPL ASSSSQPNSP
TPGSPNDRQL RRQSPTAGTM TKDSPRVSSP LREYFIGSED EHADSDRSNV SNGTTFYSPA
TSPQQRGDTP SSQGHDTGSS HRSPPTKQGT LTPEGRRDFL AKLPQRSDSL RGGNGVAPLK
STAPTASRGR GQPNRGDLSL TGSSAPTLKA QRSFDEWDGR LSPRRAEFTT DGGKRSRSVS
PKPPDVPTNV ESGTDTEADG ENEDYSEDIT QSYLNMQPSP DDERQPLSDL PPVPPPKDTK
NMIATIRQRS PSVDGPSPAI TSDEESPPAV KERFDVQGPL TEQRTSAFFS APALPPMRFS
MNGADFREIL NNLGGTNGGN NARADTGPSV AKTIEEEEAE DVAGGRTPIN PATPSDSSPD
LLSDVFDAAK KAAEHATPKA NRRAATPDTI LPRAGNSSTS NLPQASPTSP TRPDLPKRSP
HRASRSEGAI KMLQDTSPPR SSSDSADRTS PKLPSIGING RERLDSVASP PHANGSLPPE
APSQDYLDFR RPSLSKQDTS SDLVTRRLKE VVQGATDRGV DYIKIDKTFA LAIISALERK
ADQVAEISGK LDGMNRSSQH MMDGLSVALD EYSQEHNARK NAEAEISRLK IELSGQAARL
SALTSDDRRR EVHRQLSKEI TDNLSGLERD LSKLKVERDL TLAEVEELSA TKASSPEGEE
APAATVSRSL TVRLDKIKRQ YQTELVPLTE QKEELMREIR ELKDARDCFI EETAVLNRRN
EELAHLNAEY ERRAESSNSS QPKIKSITPP QPKQSFDTWR SRPPAAPPMV NATSTASTAS
TATLYDESSD ESRTVRLNGQ DTPQPKGRGI QLRWPGNKVK DLSAMQGTVN GDGKGKKRVE
HTFQQLSVLK FGMKCDHCGD KMWGSQLRCS GCAISIHGRC VATVQSACNR VEEQEESITQ
PALLQRSMFG RDLVEQVHAD AKGGDRFVPV IVEKCIDAVD TLAMDYEGIY RKSGGSGQSK
AITQLFERGN YSAFDLRDSE TFNDISSVTS VMKNYFRALP NPLLTFDLHD AFVKAAGYRE
PQAKAEALTT LVKQLPSEHF YTLGHLMLHL NRVQNNSAIN KMTARNLGVV FGPTLMRSSD
PSQEFTDMAG KTLAIEWLIE NAPAVFPAL
//
