ID A0A0H2SEN3_9AGAM Unreviewed; 857 AA.
AC A0A0H2SEN3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KLO20188.1};
GN ORFNames=SCHPADRAFT_884923 {ECO:0000313|EMBL:KLO20188.1};
OS Schizopora paradoxa.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Hymenochaetales; Schizoporaceae; Schizopora.
OX NCBI_TaxID=27342 {ECO:0000313|EMBL:KLO20188.1, ECO:0000313|Proteomes:UP000053477};
RN [1] {ECO:0000313|EMBL:KLO20188.1, ECO:0000313|Proteomes:UP000053477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KUC8140 {ECO:0000313|EMBL:KLO20188.1,
RC ECO:0000313|Proteomes:UP000053477};
RG DOE Joint Genome Institute;
RA Min B., Park H., Jang Y., Kim J.-J., Kim K.H., Pangilinan J., Lipzen A.,
RA Riley R., Grigoriev I.V., Spatafora J.W., Choi I.-G.;
RT "Complete genome sequence of Schizopora paradoxa KUC8140, a cosmopolitan
RT wood degrader in East Asia.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ085883; KLO20188.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H2SEN3; -.
DR STRING; 27342.A0A0H2SEN3; -.
DR InParanoid; A0A0H2SEN3; -.
DR OrthoDB; 1654263at2759; -.
DR Proteomes; UP000053477; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053477};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 55..114
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 416..550
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 583..841
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 207..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..277
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 96207 MW; 710D9D9F19319453 CRC64;
MLQRMQLSID PYYGRAVDGY EASSSASSSP SFSLSPLLDM SSNTTRTLFS PSSEWRLCFV
LCLYEFTSDD PDHLPFQKGE ILEIVKKEDS GWWAALRREK IGWIPSAFVT QITDEFAGSL
RHIREDLRVY HYEAERKYNS ISAPVSALSR SVDDTLHPAY IRQAHMQDDE WVPLTDAGGK
VPFVHYVSPS GLVANGFLDD SLHPLCDSIP HSPPQQPSLL DGYSTSESES ELESVPDLGD
NSMDHGQEPV ICPSSPATPM PHPHMPKIEP LHINKPTPPT PGSTSSSSST DRSSILFRSR
SDSAPTTPAS VRRTRRQPIL LGDHLSLSSL SDFMETKRRT GVDRINTTLP HKRSESDLDL
SDNDFKRSPA TRRADKVRQL LGDDDAQAFH NAKQAQANLP WYLQPSYTAD EIKLEYDGSV
RAGTLSSLVE RLTVDPLTLK QDNLYRNAFL TTYHTFTTPS EFFDLLVEQY QIDHPPGLSD
DEFYEWKERK LRPVQKRVLA IMTIWLEEYD LLQDGPGLGL RLREFLQLIQ SPPNLALTAK
LILQSLERLS NSLTRARSVS PTATPSKRRK ISRGGKNDLI RIDPTDLAEQ LALFEYRLYI
KVQPKDCILW SKTQTGEAVA NLIEFCSTHD RIAGWVKSSI LQNEGLGKRA DTVDFWIRVA
EKCRSLNNFA SMTAIVAALT SAMISRLHLT WAHVGRGTQL QPLARLNEPA SNFSAYRALH
QVTQPPCVPF IAVFLTDIVH IQDQMRDTVS FPLSSASTPL TATAVSTPTV STTSERTEDL
VNFVKRLKWY DSVESIVRFQ KKGYEIVENT SMMSFITDQL SLSGARDETV LWTRSAELQQ
NEMAHADIRK GLEAAGF
//
