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Database: UniProt
Entry: A0A0H2USH5_SHIFL
LinkDB: A0A0H2USH5_SHIFL
Original site: A0A0H2USH5_SHIFL 
ID   A0A0H2USH5_SHIFL        Unreviewed;      1166 AA.
AC   A0A0H2USH5;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   07-OCT-2020, entry version 29.
DE   SubName: Full=OriT nicking and unwinding protein {ECO:0000313|EMBL:AAL72418.1};
GN   ORFNames=SF_p0249 {ECO:0000313|EMBL:AAL72418.1};
OS   Shigella flexneri.
OG   Plasmid pCP301 {ECO:0000313|EMBL:AAL72418.1,
OG   ECO:0000313|Proteomes:UP000001006}.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623 {ECO:0000313|EMBL:AAL72418.1, ECO:0000313|Proteomes:UP000001006};
RN   [1] {ECO:0000313|EMBL:AAL72418.1, ECO:0000313|Proteomes:UP000001006}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a {ECO:0000313|Proteomes:UP000001006};
RC   PLASMID=Plasmid pCP301 {ECO:0000313|Proteomes:UP000001006};
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
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DR   EMBL; AF386526; AAL72418.1; -; Genomic_DNA.
DR   RefSeq; NP_858382.1; NC_004851.1.
DR   EnsemblBacteria; AAL72418; AAL72418; SF_p0249.
DR   GeneID; 1238121; -.
DR   KEGG; sfl:CP0249; -.
DR   PATRIC; fig|198214.7.peg.5510; -.
DR   HOGENOM; CLU_001748_2_0_6; -.
DR   OMA; STWETHR; -.
DR   Proteomes; UP000001006; Plasmid pCP301.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0000746; P:conjugation; IEA:InterPro.
DR   InterPro; IPR014129; Conjug_relaxase_TraI.
DR   InterPro; IPR009767; DNA_helicase_TraI.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR040668; TraI_2B.
DR   InterPro; IPR040987; TraI_N.
DR   Pfam; PF18272; ssDNA_TraI_N; 1.
DR   Pfam; PF07057; TraI; 1.
DR   Pfam; PF18340; TraI_2B; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02760; TraI_TIGR; 1.
PE   4: Predicted;
KW   Plasmid {ECO:0000313|EMBL:AAL72418.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001006}.
FT   DOMAIN          2..36
FT                   /note="ssDNA_TraI_N"
FT                   /evidence="ECO:0000259|Pfam:PF18272"
FT   DOMAIN          43..122
FT                   /note="TraI_2B"
FT                   /evidence="ECO:0000259|Pfam:PF18340"
FT   DOMAIN          844..966
FT                   /note="TraI"
FT                   /evidence="ECO:0000259|Pfam:PF07057"
SQ   SEQUENCE   1166 AA;  127238 MW;  2142E1C22D29DC35 CRC64;
     MKAGEESVAQ VSGVREQAIL TQAIRSELKT QGVLGHPEVT MTALSPVWLD SRSRYLRDMY
     RPGMVMEQWN PETRSHDRYV TERVTAQSHS LTLRNAQGET QVVRISSLDS SWSLFRPEKM
     PVADGERLRV TGKIPGLRVS GGDRLQVASV SEDAMTVVVP GRAEPATLPV SDSPFTALKL
     ENGWVETPGH SVSDSATVFA SVTQMAMDNA TLNGLARSGR DVRLYSSLDE TRTAEKLARH
     PSFTVVSEQI KARAGETLLE TAISLQKAGL HTPAQQAIHL ALPVLESKNL AFSMVDLLTE
     AKSFAAEGTG FADLGGEINA QIKRGDLLYV DVAKGYGTGL LVSRASYEAE KSILRHILEG
     KEAVTPLMER VPGELMEKLT SGQRAATRMI LETSDRFTVV QGYAGVGKTT QFRAVMSAVN
     MLPESERPRV VGLGPTHRAV GEMRSAGVDA QTLASFLHDT QLQQRSGETP DFSNTLFLLD
     ESSMVGNTDM ARAYALIAAG GGRAVASGDT DQLQAIAPGQ PFRLQQTRSA ADVVIMKEIV
     RQTPELREAV YSLINRDVER ALSGLERVKP SQVPRLEGAW APEHSVTEFS HSQEAKLAEA
     QQKAMLKGEA FPDVPMTLYE AIVRDYTGRT PEAREQTLIV THLNEDRRVL NSMIHDAREK
     AGELGKVQVM VPVLNTANIR DGELRRLSTW ENNPDALALV DNVYHRIAGI SKDDGLITLQ
     DAEGNTRLIS PREAVAEGVT LYTPDTIRVG TGDRIRFTKS DRERGYVANS VWTVTAVSGD
     SVTLSDGQQT RVIRPGQERA EQHIDLAYAI TAHGAQGASE TFAIALEGTE GNRKLMAGFE
     SAYVALSRMK QHVQVYTDNR QGWTDAINNA VQKGTAHDVF EPKPDREVMN AERLFSTARE
     LRDVAAGRAV LRQAGLAGGD SPARFIAPGR KYPQPYVALP AFDRNGKSAG IWLNPLTTDD
     GNGLRGFSGE GRVKGSGDAQ FVALQGSRNG ESLLADNMQD GVRIARDNPD SGVVVRIAGE
     GRPWNPGAIT GGRVWGDIPD NSVQPGAGNG EPVTAEVLAQ RQAEEAIRRE TERRADEIVR
     KMAENKPDLP DGKTEQAVRE IAGQERDRAA ITEREAALPE SVLREPQRVR EAVREVAREN
     LLQERLQQME RDMVRDLQKE KTPGGD
//
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