ID A0A0H2VWE7_SHIFL Unreviewed; 379 AA.
AC A0A0H2VWE7; A0A2G3EZM9; Q7C0Z9; Q83QZ7;
DT 23-MAY-2018, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Polysaccharide export protein {ECO:0000313|EMBL:AAN43663.1};
GN Name=wza {ECO:0000313|EMBL:AAN43663.1};
GN OrderedLocusNames=SF2126 {ECO:0000313|EMBL:AAN43663.1};
OS Shigella flexneri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623 {ECO:0000313|EMBL:AAN43663.1, ECO:0000313|Proteomes:UP000001006};
RN [1] {ECO:0000313|EMBL:AAN43663.1, ECO:0000313|Proteomes:UP000001006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a {ECO:0000313|Proteomes:UP000001006};
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004571}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004571}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family.
CC {ECO:0000256|ARBA:ARBA00009450}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005674; AAN43663.1; -; Genomic_DNA.
DR RefSeq; NP_707956.1; NC_004337.2.
DR RefSeq; WP_000978092.1; NZ_WPGW01000038.1.
DR AlphaFoldDB; A0A0H2VWE7; -.
DR SMR; A0A0H2VWE7; -.
DR PaxDb; 198214-SF2126; -.
DR GeneID; 1025325; -.
DR KEGG; sfl:SF2126; -.
DR PATRIC; fig|198214.7.peg.2536; -.
DR Proteomes; UP000001006; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.70; -; 1.
DR Gene3D; 3.10.560.10; Outer membrane lipoprotein wza domain like; 2.
DR Gene3D; 3.30.1950.10; wza like domain; 1.
DR InterPro; IPR049712; Poly_export.
DR InterPro; IPR003715; Poly_export_N.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR040716; Wza_C.
DR PANTHER; PTHR33619; POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED; 1.
DR PANTHER; PTHR33619:SF5; POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED; 1.
DR Pfam; PF02563; Poly_export; 1.
DR Pfam; PF10531; SLBB; 1.
DR Pfam; PF18412; Wza_C; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Polysaccharide transport {ECO:0000256|ARBA:ARBA00023047};
KW Porin {ECO:0000256|ARBA:ARBA00023114};
KW Reference proteome {ECO:0000313|Proteomes:UP000001006};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..379
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030007345"
FT DOMAIN 81..165
FT /note="Polysaccharide export protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02563"
FT DOMAIN 173..220
FT /note="Soluble ligand binding"
FT /evidence="ECO:0000259|Pfam:PF10531"
FT DOMAIN 347..376
FT /note="Outer-membrane lipoprotein Wza C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18412"
SQ SEQUENCE 379 AA; 41924 MW; C16F897C0F1364C5 CRC64;
MMKSKMKLMP LLVSVTLISG CTVLPGSNMS TMGKDVIKQQ DADFDLDKMV NVYPLTPRLI
DQLRPRPNVA RPNMTLESEI ANYQYRVGPG DVLNVTVWDH PELTTPAGQY RSSSDTGNWV
QPDGTMFYPY IGKVHVVGKT LAEIRSDITG RLATYIADPQ VDVNIAAFRS QKAYISGQVN
KSGQQAITNV PLTILDAINA AGGLTDTADW RNVVLTHNGR EERISLQALM QNGDLNQNRL
LYPGDILYVP RNDDLKVFVM GEVKKQSTLK MDFSGMTLTE ALANAEGIDM TTSNASGIFV
IRPLKGEGGR NGKIANIYQL DMSDATSLVM ATEFRLQPYD VVYVTTAPVS RWNRLINQLL
PTISGVRYMT DTASDIHNW
//
