ID A0A0H3CBK6_CAUVN Unreviewed; 504 AA.
AC A0A0H3CBK6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Sulfite reductase (NADPH) flavoprotein alpha-component {ECO:0000313|EMBL:ACL96624.1};
DE EC=1.8.1.2 {ECO:0000313|EMBL:ACL96624.1};
GN OrderedLocusNames=CCNA_03159 {ECO:0000313|EMBL:ACL96624.1};
OS Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=565050 {ECO:0000313|EMBL:ACL96624.1, ECO:0000313|Proteomes:UP000001364};
RN [1] {ECO:0000313|EMBL:ACL96624.1, ECO:0000313|Proteomes:UP000001364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA1000 / CB15N {ECO:0000313|Proteomes:UP000001364};
RX PubMed=20472802; DOI=10.1128/JB.00255-10;
RA Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA Walunas T.L., Crosson S.;
RT "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL J. Bacteriol. 192:3678-3688(2010).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; CP001340; ACL96624.1; -; Genomic_DNA.
DR RefSeq; WP_010920899.1; NC_011916.1.
DR RefSeq; YP_002518532.1; NC_011916.1.
DR AlphaFoldDB; A0A0H3CBK6; -.
DR SMR; A0A0H3CBK6; -.
DR GeneID; 7330997; -.
DR KEGG; ccs:CCNA_03159; -.
DR PATRIC; fig|565050.3.peg.3085; -.
DR HOGENOM; CLU_001570_17_7_5; -.
DR OrthoDB; 9791166at2; -.
DR PhylomeDB; A0A0H3CBK6; -.
DR Proteomes; UP000001364; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0004783; F:sulfite reductase (NADPH) activity; IEA:UniProtKB-EC.
DR CDD; cd06200; SiR_like1; 1.
DR Gene3D; 3.40.50.360; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR001094; Flavdoxin-like.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR19384:SF128; NADPH OXIDOREDUCTASE A; 1.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00258; Flavodoxin_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR PRINTS; PR00369; FLAVODOXIN.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023192};
KW Cysteine biosynthesis {ECO:0000256|ARBA:ARBA00023192};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:ACL96624.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001364};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022982}.
FT TRANSMEM 14..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..192
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50902"
FT DOMAIN 206..365
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 504 AA; 54240 MW; 159EE54FE3B2B443 CRC64;
MPDLAFLPPE ARRWVWAGVV VALYALFCLA IALREAWRGR QARKAADALS QGSGEPVLVA
YASQTGFAEE LATATAKALA DTGAPVTLKD LSAVTAGDLA GRALFVVSTT GEGDAPDPAR
AFIRDVMKDE ADLSALRYGV LALGDSSYAH YCAFGRSLDA WLSGRGGQPL FDRVEVDDAD
PAALRHWQGQ LATLTGVTDA PDWTRPTYDA WTLAERTLLN PGSPGGEAWH LRLTPPKGAV
WQAGDIVEIG PRNDPAQVAA LIAALDLPAE AADTLAGLRL PQDAAALDAL RGLPLEALAE
RLTALPHREY SIASLPDDGG VELIVRLMTR ADGAPGLGSG WLCRHAPIGA AIEARVRVNR
SFHAPETKRP LILIGSGTGL AGLRAHLKAR AAAGVRWNWL IFGERTAAHD YFHRAELEAW
QASGLLDRLD LAFSRDQAER VYVQHRLRES ADILRRWVAN GAAIYVCGSL EGMSREAHTA
LVEILGAPML ERLTDEGRYR RDVY
//
