ID A0A0H3FTR9_KLEAK Unreviewed; 453 AA.
AC A0A0H3FTR9;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=MFS transporter {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=EAE_21385 {ECO:0000313|EMBL:AEG99180.1};
OS Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235
OS / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56)
OS (Enterobacter aerogenes).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1028307 {ECO:0000313|EMBL:AEG99180.1};
RN [1] {ECO:0000313|EMBL:AEG99180.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2190 {ECO:0000313|EMBL:AEG99180.1};
RX PubMed=22493190; DOI=10.1128/JB.00028-12;
RA Shin S.H., Kim S., Kim J.Y., Lee S., Um Y., Oh M.K., Kim Y.R., Lee J.,
RA Yang K.S.;
RT "Complete genome sequence of Enterobacter aerogenes KCTC 2190.";
RL J. Bacteriol. 194:2373-2374(2012).
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
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DR EMBL; CP002824; AEG99180.1; -; Genomic_DNA.
DR RefSeq; WP_015705741.1; NC_015663.1.
DR RefSeq; YP_004594459.1; NC_015663.1.
DR AlphaFoldDB; A0A0H3FTR9; -.
DR KEGG; eae:EAE_21385; -.
DR PATRIC; fig|1028307.3.peg.4257; -.
DR eggNOG; COG2211; Bacteria.
DR HOGENOM; CLU_027408_0_2_6; -.
DR OrthoDB; 181905at2; -.
DR Proteomes; UP000008881; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd17332; MFS_MelB_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001927; Na/Gal_symport.
DR NCBIfam; TIGR00792; gph; 1.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 453 AA; 50078 MW; AA3AE189E2C6293D CRC64;
MSTTTKLSAS YVVIGVKEKI GYGLGDFASN LSFGFVSLFL LFFYTNVYGI SAVQASLIFV
IARVIDAIFN ILIGFAIDKT QSKYGKLRPW LLYGAIPLGF LTVLCFVPFG GEAKLYFALA
SYTIYCLAYT AVNTPYSALT NRLTQHEASR SSLSVYRFVL AIVGYLIVST TADWLISPFN
DKQIGYVFAV SCFALLATFM FLACFGMTKE RVGEEDKMNA PTLREMFRAV LGNAPLIHLS
LFTVFFYIAY TVWMAIAIYF IKYIIGSEGF TATFFMIQSG AYIIGTIISE KVIALMGKKK
MALLALLIGV LGVLMQYFIA GNNLWLIMIG VCLYSITLGM GFVAMWSMIA DTVEYAEWHH
GVRSEGAIYG FFNFITKIAM AIGGGCAGWM LDLYHYDAGN VTSDAINGIN ILMTLFPGAM
FAISAIFVAC YALDENTYRD IVQKISLRKQ NAL
//
