ID A0A0H3H4N5_KLEPH Unreviewed; 323 AA.
AC A0A0H3H4N5;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:AEW63899.1};
GN OrderedLocusNames=KPHS_52010 {ECO:0000313|EMBL:AEW63899.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain HS11286).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1125630 {ECO:0000313|EMBL:AEW63899.1, ECO:0000313|Proteomes:UP000007841};
RN [1] {ECO:0000313|EMBL:AEW63899.1, ECO:0000313|Proteomes:UP000007841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS11286 {ECO:0000313|EMBL:AEW63899.1,
RC ECO:0000313|Proteomes:UP000007841};
RX PubMed=22408243; DOI=10.1128/JB.00043-12;
RA Liu P., Li P., Jiang X., Bi D., Xie Y., Tai C., Deng Z., Rajakumar K.,
RA Ou H.Y.;
RT "Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae
RT HS11286, a multidrug-resistant strain isolated from human sputum.";
RL J. Bacteriol. 194:1841-1842(2012).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP003200; AEW63899.1; -; Genomic_DNA.
DR RefSeq; WP_014343450.1; NC_016845.1.
DR RefSeq; YP_005229501.1; NC_016845.1.
DR AlphaFoldDB; A0A0H3H4N5; -.
DR STRING; 1125630.KPHS_52010; -.
DR GeneID; 11850273; -.
DR KEGG; kpm:KPHS_52010; -.
DR PATRIC; fig|1125630.4.peg.5085; -.
DR HOGENOM; CLU_039613_16_2_6; -.
DR Proteomes; UP000007841; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08471; PBP2_CrgA_like_2; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537:SF5; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED; 1.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007841}.
FT DOMAIN 21..78
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 323 AA; 35426 MW; E4600D1F3735130A CRC64;
MKNDNTGKVA IIFPQNGRIM DRLSAMALLV KVTELGSMSA AARALNMPLT TVSRHIGELE
SALGVRLLAR TTRKLTLTDA GVDYVAAARR ILEEVENAER QATGEYQEPK GELVISAPTM
FGRQHVLPVI SEFIARYPLI RVRLLLSDRN ADLVSDHVDL AVRIGDLADS SMVATRLGTM
RIVACAHPAL LAKYGEPQRP RDLAALPIIR IESPMPYRGW RFRAAEREDQ LINLPPVLSV
TTPESAADAA RLGVGVARLL HYQALDGLRH GELRLLLENV EPDPAPVHLL YTARDLAPLK
LRKFIDFAAP ALRQALLRIA GAA
//
