UniProt: A0A0H3J863

Database: UniProt
Entry: A0A0H3J863_CLOPA

LinkDB:  A0A0H3J863_CLOPA 
Original site:  A0A0H3J863_CLOPA

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Ontology (3)   
   GO (3)   
Gene (3)   
   KEGG GENES (2)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   EMBL (2)   
Protein domain (5)   
   InterPro (4)   
   Pfam (1)   
Literature (2)   
   PubMed (2)   
All databases (16)   

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ID   A0A0H3J863_CLOPA        Unreviewed;       317 AA.
AC   A0A0H3J863;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN   Name=corA {ECO:0000256|RuleBase:RU362010,
GN   ECO:0000313|EMBL:AJA53622.1};
GN   ORFNames=CLPA_c35780 {ECO:0000313|EMBL:AJA53622.1}, CP6013_03610
GN   {ECO:0000313|EMBL:KRU14352.1};
OS   Clostridium pasteurianum DSM 525 = ATCC 6013.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262449 {ECO:0000313|EMBL:AJA53622.1, ECO:0000313|Proteomes:UP000030905};
RN   [1] {ECO:0000313|EMBL:AJA53622.1, ECO:0000313|Proteomes:UP000030905}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 525 {ECO:0000313|EMBL:AJA53622.1}, and DSM 525 / ATCC 6013
RC   {ECO:0000313|Proteomes:UP000030905};
RX   PubMed=25700415;
RA   Poehlein A., Grosse-Honebrink A., Zhang Y., Minton N.P., Daniel R.;
RT   "Complete Genome Sequence of the Nitrogen-Fixing and Solvent-Producing
RT   Clostridium pasteurianum DSM 525.";
RL   Genome Announc. 3:e01591-e01514(2015).
RN   [2] {ECO:0000313|EMBL:KRU14352.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 6013 {ECO:0000313|EMBL:KRU14352.1};
RA   Pyne M.E., Utturkar S.M., Brown S.D., Moo-Young M., Chung D.A., Chou P.C.;
RT   "Improved Draft Genome Sequence of Clostridium pasteurianum Strain ATCC
RT   6013 (DSM 525) Using a Hybrid Next-Generation Sequencing Approach.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KRU14352.1, ECO:0000313|Proteomes:UP000028042}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6013 {ECO:0000313|EMBL:KRU14352.1,
RC   ECO:0000313|Proteomes:UP000028042};
RX   PubMed=25103768;
RA   Pyne M.E., Utturkar S., Brown S.D., Moo-Young M., Chung D.A., Chou C.P.;
RT   "Improved Draft Genome Sequence of Clostridium pasteurianum Strain ATCC
RT   6013 (DSM 525) Using a Hybrid Next-Generation Sequencing Approach.";
RL   Genome Announc. 2:0-0(0).
CC   -!- FUNCTION: Mediates influx of magnesium ions.
CC       {ECO:0000256|RuleBase:RU362010}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
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DR   EMBL; CP009268; AJA53622.1; -; Genomic_DNA.
DR   EMBL; JPGY02000001; KRU14352.1; -; Genomic_DNA.
DR   RefSeq; WP_003445743.1; NZ_JPGY02000001.1.
DR   AlphaFoldDB; A0A0H3J863; -.
DR   GeneID; 76627929; -.
DR   KEGG; cpae:CPAST_c35780; -.
DR   KEGG; cpat:CLPA_c35780; -.
DR   PATRIC; fig|1262449.3.peg.2483; -.
DR   eggNOG; COG0598; Bacteria.
DR   Proteomes; UP000028042; Unassembled WGS sequence.
DR   Proteomes; UP000030905; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12831; TmCorA-like_u2; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   NCBIfam; TIGR00383; corA; 1.
DR   PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU362010};
KW   Ion transport {ECO:0000256|RuleBase:RU362010};
KW   Magnesium {ECO:0000256|RuleBase:RU362010};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030905};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362010};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT   TRANSMEM        255..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
SQ   SEQUENCE   317 AA;  37850 MW;  FF99A2881D94D7EB CRC64;
     MIRILAITNN LKPIYNLTIE EIDSKDIKWY WIDFNNPTNN ETNLLSNYFH FHSLAIEDCI
     SVLNSPKLDY YDDYDFFVFN ALDKNTLKPL EVDIFVNEKY VVSYHKQVLN ELDEAWKKAN
     MKEGDWGNGT TYIVHQILDK IVDNFFPAVY KIEDILDDIE NKEEDKSIYD LIGSIFQIRK
     ELLVLRKTIN SMRDLLYRML NSERLRNFHK DKIYFSDIYD HLLKLSSMIE SSREMTADIR
     DNYLSVNSAK MNRNMMVLTV ITTIFIPLTF IAGVYGMNFR YMPELNWRYG YFAVWIVMLI
     IAITMYLWFK NKGWMDK
//

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