UniProt: A0A0H3KJP4

Database: UniProt
Entry: A0A0H3KJP4_BURM1

LinkDB:  A0A0H3KJP4_BURM1 
Original site:  A0A0H3KJP4_BURM1

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Ontology (3)   
   GO (3)   
Gene (1)   
   KEGG GENES (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (5)   
   InterPro (4)   
   Pfam (1)   
All databases (11)   

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ID   A0A0H3KJP4_BURM1        Unreviewed;       325 AA.
AC   A0A0H3KJP4;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN   Name=corA {ECO:0000256|RuleBase:RU362010};
GN   OrderedLocusNames=BMULJ_01705 {ECO:0000313|EMBL:BAG43625.1};
OS   Burkholderia multivorans (strain ATCC 17616 / 249).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=395019 {ECO:0000313|EMBL:BAG43625.1, ECO:0000313|Proteomes:UP000008815};
RN   [1] {ECO:0000313|EMBL:BAG43625.1, ECO:0000313|Proteomes:UP000008815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17616 / 249 {ECO:0000313|Proteomes:UP000008815};
RA   Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E.,
RA   Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N.,
RA   Hattori M., Tsuda M.;
RT   "Complete genome sequence of Burkholderia multivorans ATCC 17616.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates influx of magnesium ions.
CC       {ECO:0000256|RuleBase:RU362010}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
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DR   EMBL; AP009385; BAG43625.1; -; Genomic_DNA.
DR   RefSeq; WP_012213312.1; NC_010804.1.
DR   AlphaFoldDB; A0A0H3KJP4; -.
DR   STRING; 395019.BMULJ_01705; -.
DR   KEGG; bmj:BMULJ_01705; -.
DR   eggNOG; COG0598; Bacteria.
DR   HOGENOM; CLU_007127_0_2_4; -.
DR   Proteomes; UP000008815; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12830; MtCorA-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   NCBIfam; TIGR00383; corA; 1.
DR   PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU362010};
KW   Ion transport {ECO:0000256|RuleBase:RU362010};
KW   Magnesium {ECO:0000256|RuleBase:RU362010};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008815};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362010};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT   TRANSMEM        268..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
FT   TRANSMEM        299..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
SQ   SEQUENCE   325 AA;  37184 MW;  A6A99F1E455E2441 CRC64;
     MLINCAAYQD GRKLADIEIE AISDYVSKPE CFVWVALKDP TPEELELMGE EFGLHELALE
     DARKGHQRPK IEEYGDSLFA VLHTVELDED DEFKVGELNL FVGPNYVLSI RNHTEQDFRE
     VRKRCEREPE LLREGSAFVF YALMDQVVDR YFPILETLGN ELDELEDRIF AKATTASSRA
     IIEDLYSLKR RLVMLYQHTA PLIEPLAKLT GGRIPNVCSG MVNYFRDVYD HLQRIVKTIE
     GRREMVVTAI QVNLGMISLA ENEVTKRLGS FAALFAIPTM IAGIYGMNFA NMPELHLKYG
     FYGCIAVMVA ADLALWWRFK RAGWL
//

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