ID A0A0H3KTV3_BURM1 Unreviewed; 337 AA.
AC A0A0H3KTV3;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Threonine aldolase {ECO:0000313|EMBL:BAG47053.1};
DE EC=4.1.2.5 {ECO:0000313|EMBL:BAG47053.1};
GN Name=ltaA {ECO:0000313|EMBL:BAG47053.1};
GN OrderedLocusNames=BMULJ_05215 {ECO:0000313|EMBL:BAG47053.1};
OS Burkholderia multivorans (strain ATCC 17616 / 249).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=395019 {ECO:0000313|EMBL:BAG47053.1, ECO:0000313|Proteomes:UP000008815};
RN [1] {ECO:0000313|EMBL:BAG47053.1, ECO:0000313|Proteomes:UP000008815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17616 / 249 {ECO:0000313|Proteomes:UP000008815};
RA Ohtsubo Y., Yamashita A., Kurokawa K., Takami H., Yuhara S., Nishiyama E.,
RA Endo R., Miyazaki R., Ono A., Yano K., Ito M., Sota M., Yuji N.,
RA Hattori M., Tsuda M.;
RT "Complete genome sequence of Burkholderia multivorans ATCC 17616.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; AP009386; BAG47053.1; -; Genomic_DNA.
DR RefSeq; WP_012216292.1; NC_010805.1.
DR AlphaFoldDB; A0A0H3KTV3; -.
DR STRING; 395019.BMULJ_05215; -.
DR KEGG; bmj:BMULJ_05215; -.
DR eggNOG; COG2008; Bacteria.
DR HOGENOM; CLU_029381_0_3_4; -.
DR Proteomes; UP000008815; Chromosome 2.
DR GO; GO:0004793; F:threonine aldolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:BAG47053.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008815}.
FT DOMAIN 3..283
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 197
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 337 AA; 35740 MW; A9F340FC9294FAF1 CRC64;
MIDLRSDTVT RPSQAMLAAM TAAEVGDDVW GDDPTVLRLQ AATAERAGKE AGLFFPSGTQ
SNLAALMAHC ERGDEYIVGQ LAHTYKYEGG GAAVLGSIQP QPIENAPDGT LPLAKIAAAI
KPLDNHFART RLLALENTIG GQVLPEGYVQ EAVAFARSRG LSAHLDGARV CNAAVASGRS
IAELCAPFDT VSICFSKGLG APVGSVLVGS RALIERAQRW RKVLGGGMRQ SGILAAACLY
ALDHNVERLA DDHANAAHLA EGLARIEPVK VLSQATNMVF AQFPEADCAP LEAWLKARGI
LTQMLYASRF VTHCDVSRAD IDTFIDAVGA YFAQRRA
//
