ID A0A0H4C2D4_9ACTN Unreviewed; 1007 AA.
AC A0A0H4C2D4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Phosphodiesterase {ECO:0000313|EMBL:AKN69967.1};
GN ORFNames=QR97_09090 {ECO:0000313|EMBL:AKN69967.1};
OS Streptomyces sp. PBH53.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1577075 {ECO:0000313|EMBL:AKN69967.1, ECO:0000313|Proteomes:UP000036399};
RN [1] {ECO:0000313|EMBL:AKN69967.1, ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|EMBL:AKN69967.1,
RC ECO:0000313|Proteomes:UP000036399};
RX PubMed=26227608;
RA Gosse J.T., Hill P., Dowd S.E., Boddy C.N.;
RT "Draft Genome Sequence of Streptomyces sp. Strain PBH53, Isolated from an
RT Urban Environment.";
RL Genome Announc. 3:e00859-e00815(2015).
RN [2] {ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|Proteomes:UP000036399};
RA Gosse J.T., Boddy C.N., Hill P.B.;
RT "Draft Genome Sequence of Streptomyces sp. strain PBH53, isolated from
RT urban environment.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011799; AKN69967.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4C2D4; -.
DR STRING; 1577075.QR97_09090; -.
DR PATRIC; fig|1577075.3.peg.1857; -.
DR Proteomes; UP000036399; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036399};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 398..468
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 558..696
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 705..959
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 107418 MW; FE55F7975045087F CRC64;
MSAPPSVTTT LDGAVRAPHP HDEAPPPRRP AADDRGRLAE QLVLALICAA YAVGAAFDWG
TDEVALIMGD FGLSAAAGTA AVSCFLYARS RRVRFRSAWL LFALSSTMAA LGNAVWGWYE
VVLGRTVPSP SSADVFFLCF APPAIVGLLV LAKRPVTRAG WICLGLDAWL IGGSLLTLSW
SLALAQAARI DGSSVAHAAL SLAYPLLDIA LVSMVLALHF RRAPGNRTAV NTAIGALALT
VMCDALFTSP LLHSSYRSGQ LLDAGWFAGS LLLAYAPWAA PRRGSAREAR ATDGHTRVVH
EHVPGQRSTG HHPPLLPAPG GELGRYPTGR PLTGSLAALT PYLAAAVCTL GILYNVLNGR
RPDHVVLITA GAVVLALVIR QGIMLLDNIT LTQELAQKEN HFRSLVQGSS DVIMIAAPNG
ILRYVSPAAA GVYGRPAEEL VGTELAGLIH PEDLGCVVHE VRRFLAASPL EEPTTRIECR
FRSGDGGWLN VESTVNRHHG GLIFNSRDVT ERVRLQAQLQ HNAEHDPLTD LPNRALFTKR
VQQALSGRRA TDRGAALRGT AVLFIDLDGF KAVNDTIGHQ AGDELLIQAA RRLQDAVRQG
DTASRLGGDE FAALIVGDGT RDRAARERNI LELADRLRVT LSQPYAIDGN DVRVNASIGV
AFAEPGLGAG ELLRNADLAM YRAKSAGKGR VELYKPQMQQ DVVRKAELAT RLRAALHDGE
FALLHQPVVG LQNGRITAVS AQARWRSSQG VLFTPAEFLR VAEDGDKTAE LERWILQQAV
EQAAERAATG LVVPVAVRMS ARRLLDRSMP LGSVEALLTR HGLPPGALVI ELSDTDPRVP
LDELERRLTA LSRLGVRIAL DGFGSGYAAI TALRRLPVDI LKLDRSLVEG VVESARLHKI
TSGLLRIAGD LGLQSVAEGV DLPEQVVALR AMGCTHGQGM AFAGPLDEYR LRRALGSGHF
PVPHAPAEPA FAGAASEPQG RVGVESARRS EGLSTVAVST PTGGPRR
//
