ID A0A0H4C6B1_9ACTN Unreviewed; 601 AA.
AC A0A0H4C6B1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:AKN72593.1};
GN ORFNames=QR97_25020 {ECO:0000313|EMBL:AKN72593.1};
OS Streptomyces sp. PBH53.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1577075 {ECO:0000313|EMBL:AKN72593.1, ECO:0000313|Proteomes:UP000036399};
RN [1] {ECO:0000313|EMBL:AKN72593.1, ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|EMBL:AKN72593.1,
RC ECO:0000313|Proteomes:UP000036399};
RX PubMed=26227608;
RA Gosse J.T., Hill P., Dowd S.E., Boddy C.N.;
RT "Draft Genome Sequence of Streptomyces sp. Strain PBH53, Isolated from an
RT Urban Environment.";
RL Genome Announc. 3:e00859-e00815(2015).
RN [2] {ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|Proteomes:UP000036399};
RA Gosse J.T., Boddy C.N., Hill P.B.;
RT "Draft Genome Sequence of Streptomyces sp. strain PBH53, isolated from
RT urban environment.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011799; AKN72593.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4C6B1; -.
DR STRING; 1577075.QR97_25020; -.
DR PATRIC; fig|1577075.3.peg.5196; -.
DR Proteomes; UP000036399; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000036399}.
FT DOMAIN 18..52
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 207..297
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 489..546
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
SQ SEQUENCE 601 AA; 64285 MW; 89CE1D6BF0DB6582 CRC64;
MSQEKSVQTR DEDGYDYDVI VVGSGFGGSV SALRLTEKGY KVGVLEAGRR FTRATLPKNS
WDLKNYLWAP RLGMFGIQRI HLLGNVMVLA GAGVGGGSLN YANTLYVPPR AFFDDPQWRH
ITDWQEELKP YYDQARRMLG VRLNPTMTPS DVHLKAAAQR MGVGDTFHLA PVGVFFGDGK
DADGTAKARP GERVDDPYFG GAGPARNACT ECGECMTGCR HGAKNTLNEN YLYLAEKAGA
VVHPMTTVVS VTDDSRGGYA VATLPTDRKR KGEGRLFTAR KVVLAAGTYG TQTLLHRMKA
GGQLPYLSAR LGDLTRTNSE ALVGAQTDNR RYRRATGRPK ADFTRGVAIT SSIHPDGNTH
IEPVRYGKGS NSMGGLSILQ VPYAEGSSRV LGWLANAARH PLLVARSLSN RRWSERTIIG
LVMQSLDNSL TTYLKPGGVG KGLLTARQGH GAPNPKQIRA ATEAASALAA EINGFAGSNV
GELMGTPLTA HFLGGCPIGD SPETGVIDPY HRLYGHPGIS VVDGAAVSAN LGVNPSLTIT
AQAERAMSFW PNKGEEDPRP APGAAYERLK PVEPQAPAVP ADAFGALRLP FLGMPAVPPQ
K
//
