ID A0A0H4CF47_9ACTN Unreviewed; 520 AA.
AC A0A0H4CF47;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:AKN74592.1};
GN ORFNames=QR97_37050 {ECO:0000313|EMBL:AKN74592.1};
OS Streptomyces sp. PBH53.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1577075 {ECO:0000313|EMBL:AKN74592.1, ECO:0000313|Proteomes:UP000036399};
RN [1] {ECO:0000313|EMBL:AKN74592.1, ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|EMBL:AKN74592.1,
RC ECO:0000313|Proteomes:UP000036399};
RX PubMed=26227608;
RA Gosse J.T., Hill P., Dowd S.E., Boddy C.N.;
RT "Draft Genome Sequence of Streptomyces sp. Strain PBH53, Isolated from an
RT Urban Environment.";
RL Genome Announc. 3:e00859-e00815(2015).
RN [2] {ECO:0000313|Proteomes:UP000036399}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBH53 {ECO:0000313|Proteomes:UP000036399};
RA Gosse J.T., Boddy C.N., Hill P.B.;
RT "Draft Genome Sequence of Streptomyces sp. strain PBH53, isolated from
RT urban environment.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CP011799; AKN74592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4CF47; -.
DR STRING; 1577075.QR97_37050; -.
DR PATRIC; fig|1577075.3.peg.7792; -.
DR Proteomes; UP000036399; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000036399}.
FT DOMAIN 252..266
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
SQ SEQUENCE 520 AA; 54783 MW; A6ADD628FE955435 CRC64;
MSTYDYVIVG AGAAGCVLAA RLSEDPDVRV ALIEAGGPDS AQEIHVPAAF PQLFKSDLDW
DLDSDPEPGL GGRRTYLPRG RMFGGSSSMN AMIYIRGSRA DYDGWAAAGA TGWSYAEVLP
YFKRSEDNER GEDAFHGVGG PLTVSDGRSD HPLATAFVQA AVEAGHKAND DFNGETQFGV
GRYQLTQRGG MRCSTAVAFL HPALERPNLT VLSSARAHRV VIEGGRAVGV EVERGGTVDT
VRAEREVILS AGAYESPKLL MLSGIGPAAD LSAFGIDVVR DLPVGQGLQD HYMTLLNFRT
AAESLISAAT PENAALLQNE GRGPLTSNIG EAGGFFRSRD GLDAPDLQFH AAPSLFHQEG
LGAATEHGFA FGPCVLAPTS RGAVTLRSPR PDVAPRIVHN YLTTAEDQDA IVAGIRIALD
IAAQRAVTDL ATGLYGDTPA ASASDADLLA WARRSGQTLY HPTSTCAIGS VVDPELRVYD
VPGLRVVDAS VFPTVTRGNT NAPTVMAAEK AADLIRGAVR
//
