ID   A0A0H4IYZ0_9PROT        Unreviewed;       479 AA.
AC   A0A0H4IYZ0;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Peptidase M17 {ECO:0000313|EMBL:AKO66211.1};
GN   ORFNames=VI33_05940 {ECO:0000313|EMBL:AKO66211.1};
OS   Methylophilales bacterium MBRS-H7.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OM43 clade.
OX   NCBI_TaxID=1623450 {ECO:0000313|EMBL:AKO66211.1, ECO:0000313|Proteomes:UP000066549};
RN   [1] {ECO:0000313|EMBL:AKO66211.1, ECO:0000313|Proteomes:UP000066549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBRSH7 {ECO:0000313|EMBL:AKO66211.1,
RC   ECO:0000313|Proteomes:UP000066549};
RA   Jimenez-Infante F., Ngugi D.K., Vinu M., Alam I., Kamau A., Blom J.,
RA   Bajic V.B., Stingl U.;
RT   "Comparative analysis of the OM43 clade including a novel species from Red
RT   Sea uncovers genomic and metabolic diversity among marine methylotrophs.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
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DR   EMBL; CP011002; AKO66211.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H4IYZ0; -.
DR   PATRIC; fig|1623450.3.peg.1178; -.
DR   OrthoDB; 9809354at2; -.
DR   Proteomes; UP000066549; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00433; Peptidase_M17; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   PANTHER; PTHR11963:SF4; AMINOPEPTIDASE NPEPL1-RELATED; 1.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000066549}.
FT   DOMAIN          163..467
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00883"
SQ   SEQUENCE   479 AA;  53164 MW;  BD11BFD5991BA01C CRC64;
     MKVKINLQKK SDKMSLKSAK HYLNVIKNDK SELFSDIAKA KLKRLNMKFN DLETKFLSVD
     GDNAGHYVFI KYSSKSTFKI QTHLRKGLKN LLSENPDTIN LFCEDDDPTW NRELLYTTLL
     NSQDLPSRKS KTEKKQLKVI NFYGNLSAKD VAEIEALVEG NTLSRQLTMT PPNDLTPTHY
     RREIKKLATK RKWKFKEYNM GQLKKMGAGA FVAVGQGSEP QDAAIVHLTY QPKTFKKTIT
     LVGKGICFDT GGHNLKPSKY MFSMHEDMNG SATALGILEA AALNKLPVKI DCWLAIAQNH
     IGPKAYKQND VVKALNGKTI EIIHTDAEGR MVLADTLTLA TKTKSDAVID FATLTGCMAV
     AMGDRYSGIF SNKPELACLA VGSGQQAGER VSSFPFDEDY EEDIKSDIAD IKQCTLEGGP
     DHIHAARFLS QFLSDSKQSW LHVDLSSSNT KGGLGAAMSD VNGFGVRFGF NLIQDILKK
//