ID A0A0H4JCL1_9PROT Unreviewed; 442 AA.
AC A0A0H4JCL1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN ORFNames=VI33_06175 {ECO:0000313|EMBL:AKO66252.1};
OS Methylophilales bacterium MBRS-H7.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales; OM43 clade.
OX NCBI_TaxID=1623450 {ECO:0000313|EMBL:AKO66252.1, ECO:0000313|Proteomes:UP000066549};
RN [1] {ECO:0000313|EMBL:AKO66252.1, ECO:0000313|Proteomes:UP000066549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBRSH7 {ECO:0000313|EMBL:AKO66252.1,
RC ECO:0000313|Proteomes:UP000066549};
RA Jimenez-Infante F., Ngugi D.K., Vinu M., Alam I., Kamau A., Blom J.,
RA Bajic V.B., Stingl U.;
RT "Comparative analysis of the OM43 clade including a novel species from Red
RT Sea uncovers genomic and metabolic diversity among marine methylotrophs.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP011002; AKO66252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4JCL1; -.
DR PATRIC; fig|1623450.3.peg.1233; -.
DR OrthoDB; 9813412at2; -.
DR Proteomes; UP000066549; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000066549};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 177..229
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 442 AA; 50664 MW; 12BA37AAA32070AB CRC64;
MSFKLRLILI VNTLLILSIV LSLILIVLNS AKNTKSEILS SKQLASYAIR QSIQKNPEYI
KYLEANRTLG ISELITVRHL LIEYYNKDDL LLETNLNQNT QALTPAWFSF LLSWKQKENY
EHEIIPLNVS GKDIGYIKLT PDPTSEFNEI WEQFKNSLLV TIIFVLLINV SIFIIFSRIL
SPINQLIESF DRLAKKQFNV AVPLPKILEF NTLSRKFNVM ARQLKKNNDE IMRLNRAVVN
IQEDEKKSIS RDLHDDFAQS LAAIQAEAYV ATEKQSQAFK NVQLKKIISI SKSMIQDLRT
LLQSLNLGII DEVGIETALN DLIDQWIKKN KQKNVELEIN ITEKLDVLDK RQIINLYRII
QECLTNISKH SDSKKTSISI LEKKDQLKIM VRNNGIRKTK IKTSKLGLIG MRERVAALSG
SFSAKKIKDN FVVTVLIPLT GN
//
