ID A0A0H4P0N6_9BACI Unreviewed; 316 AA.
AC A0A0H4P0N6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Putative metal chaperoneinvolved in Zn homeostasisGTPase of COG0523 family {ECO:0000313|EMBL:AKP46535.1};
GN ORFNames=BSM4216_1253 {ECO:0000313|EMBL:AKP46535.1};
OS Bacillus smithii.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1479 {ECO:0000313|EMBL:AKP46535.1, ECO:0000313|Proteomes:UP000036353};
RN [1] {ECO:0000313|EMBL:AKP46535.1, ECO:0000313|Proteomes:UP000036353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4216 {ECO:0000313|EMBL:AKP46535.1,
RC ECO:0000313|Proteomes:UP000036353};
RA Bosma E.F., Koehorst J.J., van Hijum S.A.F.T., Renckens B., Vriesendorp B.,
RA van de Weijer A.H.P., Schaap P.J., de Vos W.M., van der Oost J.,
RA van Kranenburg R.;
RT "Complete genome sequence of thermophilic Bacillus smithii type strain DSM
RT 4216T.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP012024; AKP46535.1; -; Genomic_DNA.
DR RefSeq; WP_048622966.1; NZ_CP012024.1.
DR AlphaFoldDB; A0A0H4P0N6; -.
DR STRING; 1479.BSM4216_1253; -.
DR KEGG; bsm:BSM4216_1253; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000036353; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 4..181
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT DOMAIN 228..311
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07683"
SQ SEQUENCE 316 AA; 36384 MW; 90F3C801891D7DB3 CRC64;
MKKPVYIMIG FLGSGKTTVL LNLMEACKKR NQKPAIILNE LGSVNVESHL FEDQRVIEIL
DGCICCTIQS NFKETLDQLM KERETFDVLF IEGTGVANPI ELMEVLLQPT YSKVFDIFSI
ISVIDAGNFL SHLSIFSSSS ELIQLLKDQV QCATYIVMNK LDQVSKNKLH KIEEKLHQLV
SEEVPIHFTT FGKIPITEVF MKRFTINHLS HDRKGDVHEH VHHHAFIEAV RIENVSAASK
KTLVKWLNSL PDELYRAKGI VRLEGKEDFY QVQYSPKNVR MYSIRTRNQN MIPSMIFIGH
FAIQKIKEQF EHEFSS
//
