ID A0A0H4Q138_9FLAO Unreviewed; 337 AA.
AC A0A0H4Q138; A0A0H4QHK7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|HAMAP-Rule:MF_00268};
DE AltName: Full=Recombinase A {ECO:0000256|HAMAP-Rule:MF_00268, ECO:0000256|RuleBase:RU000526};
GN Name=recA {ECO:0000256|HAMAP-Rule:MF_00268,
GN ECO:0000313|EMBL:AKP61340.1};
GN ORFNames=C4S77_06020 {ECO:0000313|EMBL:PQL93215.1};
OS Apibacter adventoris.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Apibacter.
OX NCBI_TaxID=1679466 {ECO:0000313|EMBL:AKP61340.1};
RN [1] {ECO:0000313|EMBL:AKP61340.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WkB180 {ECO:0000313|EMBL:AKP61341.1}, and WkB301
RC {ECO:0000313|EMBL:AKP61340.1};
RX PubMed=26743158; DOI=10.1099/ijsem.0.000882;
RA Kwong W.K., Moran N.A.;
RT "Apibacter adventoris gen. nov., sp. nov., a member of the phylum
RT Bacteroidetes isolated from honey bees.";
RL Int. J. Syst. Evol. Microbiol. 66:1323-1329(2016).
RN [2] {ECO:0000313|EMBL:PQL93215.1, ECO:0000313|Proteomes:UP000238042}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WkB301 {ECO:0000313|EMBL:PQL93215.1}, and wkB301
RC {ECO:0000313|Proteomes:UP000238042};
RA Kwong W.K., Steele M.I., Moran N.A.;
RT "Genome sequences of Apibacter spp., gut symbionts of Asian honey bees.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC DNA, and the ATP-dependent hybridization of homologous single-stranded
CC DNAs. It interacts with LexA causing its activation and leading to its
CC autocatalytic cleavage. {ECO:0000256|HAMAP-Rule:MF_00268}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00268}.
CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC ECO:0000256|HAMAP-Rule:MF_00268, ECO:0000256|RuleBase:RU004527}.
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DR EMBL; KT149263; AKP61340.1; -; Genomic_DNA.
DR EMBL; KT149264; AKP61341.1; -; Genomic_DNA.
DR EMBL; PSZM01000036; PQL93215.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4Q138; -.
DR OrthoDB; 9776733at2; -.
DR Proteomes; UP000238042; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR CDD; cd00983; RecA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00268; RecA; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013765; DNA_recomb/repair_RecA.
DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049261; RecA-like_C.
DR InterPro; IPR049428; RecA-like_N.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR023400; RecA_C_sf.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02012; tigrfam_recA; 1.
DR PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR PANTHER; PTHR45900; RECA; 1.
DR Pfam; PF00154; RecA; 1.
DR Pfam; PF21096; RecA_C; 1.
DR PRINTS; PR00142; RECA.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54752; RecA protein, C-terminal domain; 1.
DR PROSITE; PS00321; RECA_1; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00268}; Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00268};
KW DNA damage {ECO:0000256|HAMAP-Rule:MF_00268,
KW ECO:0000256|RuleBase:RU004527};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP-
KW Rule:MF_00268};
KW DNA repair {ECO:0000256|HAMAP-Rule:MF_00268,
KW ECO:0000256|RuleBase:RU000526};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00268};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00268}; Reference proteome {ECO:0000313|Proteomes:UP000238042};
KW SOS response {ECO:0000256|HAMAP-Rule:MF_00268,
KW ECO:0000256|RuleBase:RU000526}.
FT DOMAIN 42..201
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 206..280
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
FT BINDING 72..79
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00268"
SQ SEQUENCE 337 AA; 36439 MW; BA9EB388CAA403EE CRC64;
MAEKEANNSD AKKKALNLIL DKLDKTYGKG AVMRMGDKPV EEIDVIPTGS FGLDLALGVG
GYPRGRVIEI FGPESSGKTT LTLHAIAEAQ KKGGVAAFID AEHAFDPTYA QHLGINLDEL
IISQPDDGEQ ALEIADNLIR SGAIDIVVID SVAALTPRAE IEGEMGDSKM GLHARLMSQA
LRKLTATINK AKCTVIFINQ LREKIGVMFG NPETTTGGNA LKFYASVRID IRKSGSPIKD
GENAIGSRVK VKVVKNKVAP PFRQTEFDIM YGEGISKVGE VLDLGVDMGI VGKSGSWFSY
QDTKLGQGRD AVKQLLKDNP ELLEEIETRI KEKLAEK
//
