ID A0A0H4VSY6_9BORD Unreviewed; 765 AA.
AC A0A0H4VSY6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=zraS {ECO:0000313|EMBL:AKQ53642.1};
GN ORFNames=ACR54_00284 {ECO:0000313|EMBL:AKQ53642.1};
OS Bordetella hinzii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=103855 {ECO:0000313|EMBL:AKQ53642.1, ECO:0000313|Proteomes:UP000036382};
RN [1] {ECO:0000313|EMBL:AKQ53642.1, ECO:0000313|Proteomes:UP000036382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F582 {ECO:0000313|EMBL:AKQ53642.1,
RC ECO:0000313|Proteomes:UP000036382};
RX PubMed=26316634;
RA Weigand M.R., Changayil S., Kulasekarapandian Y., Tondella M.L.;
RT "Complete Genome Sequences of Two Bordetella hinzii Strains Isolated from
RT Humans.";
RL Genome Announc. 3:e00965-e00915(2015).
RN [2] {ECO:0000313|Proteomes:UP000036382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F582 {ECO:0000313|Proteomes:UP000036382};
RA Weigand M.R., Changayil S., Kulasekarapandian Y., Batra D., Williams M.M.,
RA Tondella M.L.;
RT "Complete Genome Sequences of Two Bordetella hinzii Isolated from Humans.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP012076; AKQ53642.1; -; Genomic_DNA.
DR RefSeq; WP_029579751.1; NZ_LT906461.1.
DR AlphaFoldDB; A0A0H4VSY6; -.
DR STRING; 103855.ACR54_00284; -.
DR GeneID; 56619778; -.
DR KEGG; bhz:ACR54_00284; -.
DR PATRIC; fig|103855.15.peg.282; -.
DR eggNOG; COG5000; Bacteria.
DR Proteomes; UP000036382; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR017232; NtrY.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PIRSF; PIRSF037532; STHK_NtrY; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000036382};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AKQ53642.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 316..368
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 516..746
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 765 AA; 83232 MW; 4DADDD365026D90F CRC64;
MRLLLRLALI IGAVSGLSLL GLLAWSTGNA SRLAQYYDVL LILNGVFALA MFVWVVALTV
RLARQIRRRL FGARLTARFA LAFALIGVVP GALIYTLSVQ FLSRSIESWF NVRVDNALEA
GLNLGRAALD SQLADLDARA RAMASELNNL TDADIPLVLT RLREANGVQE ALVFTGSGRP
LAFSTNKFGQ LVPPTPPATV LNQLKLARGY SAAEADDPGI PGAEDGLHLR VVIPLSTPVR
FDSSLAGAGE PRWLQLMQNV PEQIAHNANR VQQGFRDYQE LALSRLGLRK LYGITLTLAL
LLAVFAAIAV ALSLSKRLVR PLLTLAAGTQ AVSVGDYRPL PEPPERDEVG QLTRSFNAMT
RQLDEARQMV ESNRRQLERS NVYLESVLAN LSSGVLAFDE SFRVTTVNQG AQNILQADLR
SVIGRPLETV DGMLEFARIV REAFSAHAAV GSERQHWQQQ FEITPAQAGA QPIILLARGT
HLRVDGRGNG YLVVFDDITE VISANRTMAW GEVARRLAHE IKNPLTPIQL SAERLAMKLA
GRLPPAEAQM LERATNTIVN QVGSLKQMVD DFREYARTPP AVMQPIDFNG LVADVLALYG
WDPVDGQARN GGPRLDVELA QGLPVIEGDL TQLRQVIHNL LANARDAVND LGDKAQVRVV
TQLTHIPHSD GSETAAVRFT VADNGSGFPP QVMQRAFEPY VTTKAHGTGL GLAIVRKIVE
EHGGRIDIAN RKEGGARVSI LLTRLAGASD TMDETLQQKH NAATQ
//
