ID A0A0H4W0Z5_9BORD Unreviewed; 327 AA.
AC A0A0H4W0Z5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=D-2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:AZW18557.1};
DE SubName: Full=Glyoxylate/hydroxypyruvate reductase B {ECO:0000313|EMBL:AKQ55855.1};
DE EC=1.1.1.79 {ECO:0000313|EMBL:AKQ55855.1};
GN Name=tkrA_1 {ECO:0000313|EMBL:AKQ55855.1};
GN ORFNames=ACR54_02540 {ECO:0000313|EMBL:AKQ55855.1}, CS347_18195
GN {ECO:0000313|EMBL:AZW18557.1};
OS Bordetella hinzii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=103855 {ECO:0000313|EMBL:AKQ55855.1, ECO:0000313|Proteomes:UP000036382};
RN [1] {ECO:0000313|EMBL:AKQ55855.1, ECO:0000313|Proteomes:UP000036382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F582 {ECO:0000313|EMBL:AKQ55855.1,
RC ECO:0000313|Proteomes:UP000036382};
RX PubMed=26316634;
RA Weigand M.R., Changayil S., Kulasekarapandian Y., Tondella M.L.;
RT "Complete Genome Sequences of Two Bordetella hinzii Strains Isolated from
RT Humans.";
RL Genome Announc. 3:e00965-e00915(2015).
RN [2] {ECO:0000313|Proteomes:UP000036382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F582 {ECO:0000313|Proteomes:UP000036382};
RA Weigand M.R., Changayil S., Kulasekarapandian Y., Batra D., Williams M.M.,
RA Tondella M.L.;
RT "Complete Genome Sequences of Two Bordetella hinzii Isolated from Humans.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000282741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H720 {ECO:0000313|Proteomes:UP000282741};
RA Weigand M.R., Loparev V., Peng Y., Bowden K.E., Tondella M.L.,
RA Williams M.M.;
RT "Whole genome sequencing of various Bordetella species.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AZW18557.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H720 {ECO:0000313|EMBL:AZW18557.1};
RX PubMed=31744907;
RA Weigand M.R., Peng Y., Batra D., Burroughs M., Davis J.K., Knipe K.,
RA Loparev V.N., Johnson T., Juieng P., Rowe L.A., Sheth M., Tang K.,
RA Unoarumhi Y., Williams M.M., Tondella M.L.;
RT "Conserved Patterns of Symmetric Inversion in the Genome Evolution of
RT Bordetella Respiratory Pathogens.";
RL mSystems 4:e00702-19(2019).
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DR EMBL; CP012076; AKQ55855.1; -; Genomic_DNA.
DR EMBL; CP024172; AZW18557.1; -; Genomic_DNA.
DR RefSeq; WP_029581113.1; NZ_LT906461.1.
DR STRING; 103855.ACR54_02540; -.
DR GeneID; 56622098; -.
DR KEGG; bhz:ACR54_02540; -.
DR PATRIC; fig|103855.14.peg.2500; -.
DR eggNOG; COG0111; Bacteria.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000036382; Chromosome.
DR Proteomes; UP000282741; Chromosome.
DR GO; GO:0030267; F:glyoxylate reductase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AKQ55855.1}; Pyruvate {ECO:0000313|EMBL:AKQ55855.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036382}.
FT DOMAIN 118..294
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 327 AA; 35430 MW; 4E65F155234AF42F CRC64;
MPPPTEAVLR ILCSDAEAPH LGQALAQAPF AWRLQRPGEA FDLAFISRDI TGRSTKFEVA
PETAVYYDAL RGNAALRWVH VHSAGADRQI YLDLHARGVA ITTSQGASDA VVAQTALAGL
LSLARKLPEL ARQQREHRWQ PLMGPRTPRD LAGQRAVIVG WGGIGQRIGA SLRALGLSIT
VVRRSGAPVP DAAQSLPYER LDEALPQADW LILACPLTPL TQNLISRQAL QRLPAHAMLI
NVARGHVVDE TALAEHLAGG RLAGAFLDVF QHEPLPADSP LWDLPNTLIT PHSAAFSSGN
ADRVREIFLD NLARLARGER LRNLVNA
//
