ID   A0A0H4W1B6_9SPHN        Unreviewed;       397 AA.
AC   A0A0H4W1B6;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 2.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE            EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN   ORFNames=CP97_08140 {ECO:0000313|EMBL:AKQ43293.2};
OS   Aurantiacibacter atlanticus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Erythrobacteraceae; Aurantiacibacter.
OX   NCBI_TaxID=1648404 {ECO:0000313|EMBL:AKQ43293.2, ECO:0000313|Proteomes:UP000059113};
RN   [1] {ECO:0000313|EMBL:AKQ43293.2, ECO:0000313|Proteomes:UP000059113}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=s21-N3 {ECO:0000313|Proteomes:UP000059113};
RX   PubMed=26220886; DOI=10.1099/ijsem.0.000481;
RA   Zhuang L., Liu Y., Wang L., Wang W., Shao Z.;
RT   "Erythrobacter atlanticus sp. nov., a bacterium from ocean sediment able to
RT   degrade polycyclic aromatic hydrocarbons.";
RL   Int. J. Syst. Evol. Microbiol. 65:3714-3719(2015).
RN   [2] {ECO:0000313|Proteomes:UP000059113}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=s21-N3 {ECO:0000313|Proteomes:UP000059113};
RA   Zhuang L., Liu Y., Shao Z.;
RT   "The complete genome sequence of Erythrobacter sp. s21-N3.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC         mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:68623; EC=5.1.3.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00036080};
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
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DR   EMBL; CP011310; AKQ43293.2; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H4W1B6; -.
DR   STRING; 1648404.CP97_08140; -.
DR   KEGG; ery:CP97_08140; -.
DR   Proteomes; UP000059113; Chromosome.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059113}.
FT   DOMAIN          37..381
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   397 AA;  42835 MW;  D7936F506887B258 CRC64;
     MVELHPEPLV GTHSVTPVLL VIGTRPEAIK MLPVVRALRA VPGVDLKVVT TGQHRQMLDQ
     VFAVFGEQPD IDLDLMTPGQ SLGAITARVM REMEMLIAQH QPGLVLVHGD TTSAMAAGLA
     AFYAHVPLGH VEAGLRSHDI QRPWPEEYNR ISIDAVADLL WAPTSIAAKN LHNERPEKRG
     TQRHIEVTGN SGIDALLHVA AGLKGDELAS IDVTLDPAKK LVLVTGHRRE SFGDGFARIC
     DALVELAARG DTQIIYPVHL NPQVKNVVEA RLGNTSAIHL IPPVDYVQMV AMMQAAHFIL
     TDSGGIQEEA PALGKPVLVM RDVTERPEAV ATGVAQLVGT EVDGIMAAAT RLLSEPDHYE
     RRAKKVFPYG DGSAAEKIAR SVSQFLKAQQ AAKEPAQ
//