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Entry: A0A0H5DNR2_9BACT
LinkDB: A0A0H5DNR2_9BACT
Original site: A0A0H5DNR2_9BACT 
ID   A0A0H5DNR2_9BACT        Unreviewed;       362 AA.
AC   A0A0H5DNR2;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   08-MAY-2019, entry version 15.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroF {ECO:0000313|EMBL:CRX38026.1};
GN   ORFNames=ELAC_0674 {ECO:0000313|EMBL:CRX38026.1};
OS   Estrella lausannensis.
OC   Bacteria; Chlamydiae; Parachlamydiales; Criblamydiaceae; Estrella.
OX   NCBI_TaxID=483423 {ECO:0000313|EMBL:CRX38026.1, ECO:0000313|Proteomes:UP000220251};
RN   [1] {ECO:0000313|EMBL:CRX38026.1, ECO:0000313|Proteomes:UP000220251}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB-30 {ECO:0000313|EMBL:CRX38026.1,
RC   ECO:0000313|Proteomes:UP000220251};
RA   Bertelli Claire;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CWGJ01000011; CRX38026.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000220251; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000220251};
KW   Reference proteome {ECO:0000313|Proteomes:UP000220251};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:CRX38026.1}.
FT   DOMAIN       32    327       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   362 AA;  40014 MW;  A4A5E77B78340000 CRC64;
     MDRLQAPIDV KNSLCLEQEE AAFIGKSRET IRSILDGEDT RKICIVGPCS IHDLSAAIEY
     AEKLKKLQAE VEETFLLVMR CYIEKPRTQL GWKGLLYDPM LDGTGNMKEG IRLARSLLIH
     LAKMRVPAAT EIIDPFLVGY FDDLISWGCI GARTSESQTH RLMASGLSMP VAFKNTTDGN
     VKVAINGIIA ASQSNAFIAL DENGSAAMRK TRGNPHCHLV LRGSHHHTNY DHIAIAQANK
     DLKDSLQKER VIIDCSHGNC RFSPDGQISP FKSVVAQMAE GNETIKGIVL ESHLFGGRQE
     LSSDPRELRY GVSITDHCLD FETTEQLILW AQEAINSKIP ESSLYPLPQS SSPCAMHETL
     PS
//
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