ID   A0A0H5E5I2_9BACT        Unreviewed;      1027 AA.
AC   A0A0H5E5I2;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:CRX38490.1};
GN   ORFNames=ELAC_1147 {ECO:0000313|EMBL:CRX38490.1};
OS   Estrella lausannensis.
OC   Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Criblamydiaceae;
OC   Estrella.
OX   NCBI_TaxID=483423 {ECO:0000313|EMBL:CRX38490.1, ECO:0000313|Proteomes:UP000220251};
RN   [1] {ECO:0000313|Proteomes:UP000220251}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIB-30 {ECO:0000313|Proteomes:UP000220251};
RA   Bertelli C.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CWGJ01000012; CRX38490.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H5E5I2; -.
DR   Proteomes; UP000220251; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF21; MULTIDRUG RESISTANCE PROTEIN MDTB; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000220251};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        327..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        422..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        454..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        519..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        857..876
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        909..934
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        955..976
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        988..1012
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1027 AA;  112481 MW;  BB5F061AD0FC0828 CRC64;
     MTTLVMLAIL LVGILSYRLL PISNLPDVNF PTISVTTRLP GASPETMANT VATPLEKQFM
     TIPGVLDVTS TNTLGNSNIT IQFDVSKDID LAAIDVQSAI TQAKPKLPPN LPQDPVFKKA
     NPSDTPIIYI ALTSSTVAQG ELYNLANTII GQRISTVEGV AQVTVYGSPS AVRVQVDPKI
     ISMLGLTLQD VSKALQAANQ NQPTGQLDGL ELSSIIQTNG QLTRASEYEN VIVSFNDEGP
     VRVRDIGRAQ DSRQNDRESE YFVDGETKEA AVVLAVLRQP GANTVRVADA IASYLPKLEK
     LIPGNVTMRV VFDRSESIKH SINDVEITLI LAFIMVVLVI FLYLGKLKNT IIPSIAMPMS
     ILGTFPIMYL MGYSLDNLSL LALTLAMGFI VDDAIVVLEN IERMVEEGMS PLEGALEGSR
     QICFTIISMT LSLVAVFIPM LFMAGIIGKL FQEFSVTLTV VTLMSGVISL SLTPMLCSLF
     MPPRKEQHEG TLGRFSARLN ERLVGWYKPL LLWALDNRWL SVATASASIV LTVLFFKILP
     LDFIPDDDIG FVVAYMEGMQ GTSSDRMHGY QRELIDVLRE QPEIESFISI ASNRDYRQGL
     NFIRLVPQEE RESSTRVIQK LMPKVAEIPG LRVYFKNVPL IDLSIGTQTK GGYQYILSGL
     NIEELYSQAE QLLSKMSAHP DVFQSISSDL ENRTPQLFVN VLRDQAARYG VSVEGIENAL
     SRSFSANRIS LIDTPTDQFD LIVEVFRKDQ YDSSTLAYTY LRNTIANPSA NPASIANANQ
     LVPMGSVATW EEGAGFNSVN HYMQFPSVTI SFNVVPGVAL GDALALLNEL ADETVKGEID
     GMVKGIGQTF EEAVDSAGLL LVFSLIAIYI ILGILYESFI HPFTILSTLP PAIFGGLATL
     WLLGMPLSLY GFLGIILLIG IVKKNGIMVV DYALEYLKKG EDARTAIVDA CVVRFRPIMM
     TTLAAICGAI PIAYAFGPGL VSRRPLGLVI IGGLIFSQLV TLFVTPVVFL YLEELREKYG
     AKPRQEE
//